At NINGBO INNO PHARMCHEM CO.,LTD., we understand that the foundation of effective drug development lies in the precise synthesis and understanding of critical chemical intermediates. One such compound making significant strides in pharmaceutical research is 6-Fluoro-4-nitro-1(3H)-isobenzofuranone, identified by its CAS number 1207453-90-4. This molecule is a prime example of a sophisticated fine chemical that serves as an indispensable building block for novel therapeutic agents, particularly in the challenging field of oncology.

The molecular structure of 6-Fluoro-4-nitro-1(3H)-isobenzofuranone is a key determinant of its utility. It features an isobenzofuranone core, functionalized with a fluorine atom at the 6-position and a nitro group at the 4-position. This specific arrangement provides a unique electronic environment and predictable reactivity, making it an ideal candidate for complex synthetic pathways. The 6-fluoro-4-nitro-1(3H)-isobenzofuranone synthesis typically involves carefully controlled reaction conditions, often starting from precursors like methyl 5-fluoro-2-methyl-3-nitrobenzoate. The methods employed aim for high yields and purity, ensuring that the intermediate meets the stringent requirements of the pharmaceutical industry.

The significance of this compound is amplified by its role as a precursor for potent drugs, such as talazoparib. The successful synthesis of talazoparib relies heavily on the consistent quality and availability of intermediates like 6-Fluoro-4-nitro-1(3H)-isobenzofuranone. Researchers frequently cite the compound's utility in organic synthesis, leveraging its reactive sites to build complex molecular architectures. The inclusion of fluorine often enhances a drug candidate's pharmacokinetic properties, including improved absorption and metabolic stability, while the nitro group can serve as a handle for further chemical modifications or contribute directly to the drug's mechanism of action.

NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supporting scientific innovation by providing access to such high-value intermediates. We recognize the critical importance of reliable suppliers for the success of research projects. By offering 6-Fluoro-4-nitro-1(3H)-isobenzofuranone, we empower scientists to explore new frontiers in drug discovery. The compound’s unique properties are vital for projects focusing on advanced pharmaceutical intermediate applications, where precision and purity are paramount.

In conclusion, the chemistry of 6-Fluoro-4-nitro-1(3H)-isobenzofuranone is a testament to the power of molecular design in modern medicine. Its well-defined synthesis and versatile reactivity make it a cornerstone for developing cutting-edge treatments. NINGBO INNO PHARMCHEM CO.,LTD. is proud to be a trusted source for this essential chemical, facilitating breakthroughs in drug development and contributing to the advancement of global health.