The Chemistry Behind Entecavir Synthesis: Focus on Intermediate N-1
The development of effective antiviral therapies, such as Entecavir for Hepatitis B, relies on sophisticated organic synthesis pathways. A fundamental building block in this process is Entecavir Intermediate N-1, scientifically known as 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one, identified by CAS number 142217-81-0. This article aims to illuminate its chemical importance and guide potential buyers.
Chemically, Entecavir Intermediate N-1 is a purine derivative featuring a complex cyclopentyl substituent with protective benzyloxy groups. These structural features are critical for guiding subsequent reactions towards the formation of the Entecavir molecule. The typical presentation as a white powder with a purity of 98% or higher (by HPLC) underscores its role as a precisely manufactured chemical entity. For R&D scientists and process chemists, sourcing this intermediate with such high purity is essential to minimize side reactions and maximize the yield of the desired API.
When considering where to buy Entecavir Intermediate N-1, it is vital to partner with a manufacturer that possesses advanced synthetic capabilities and rigorous quality control. We, as a leading Entecavir intermediate supplier in China, offer this expertise. Our production facilities are equipped to handle complex synthesis steps, ensuring that each batch of Entecavir Intermediate N-1 meets the stringent specifications required by the pharmaceutical industry. Understanding the Entecavir Intermediate N-1 price from reliable manufacturers allows for effective budget planning in drug development projects.
The strategic importance of Entecavir Intermediate N-1 in the synthesis of Entecavir cannot be overstated. Its precise molecular architecture serves as a scaffold upon which the final drug molecule is built. Therefore, the quality and availability of this intermediate directly influence the efficiency and success of Entecavir production. We are dedicated to providing a stable and high-quality supply of this critical pharmaceutical intermediate to researchers and manufacturers globally.
For those seeking to procure Entecavir Intermediate N-1, engaging with experienced chemical manufacturers is the most effective approach. We welcome your inquiries and are prepared to provide detailed product information, competitive pricing, and reliable supply chain solutions. Discover the advantages of partnering with a committed Entecavir intermediate manufacturer to support your vital pharmaceutical synthesis needs.
Perspectives & Insights
Quantum Pioneer 24
“Chemically, Entecavir Intermediate N-1 is a purine derivative featuring a complex cyclopentyl substituent with protective benzyloxy groups.”
Bio Explorer X
“These structural features are critical for guiding subsequent reactions towards the formation of the Entecavir molecule.”
Nano Catalyst AI
“The typical presentation as a white powder with a purity of 98% or higher (by HPLC) underscores its role as a precisely manufactured chemical entity.”