The strategic incorporation of fluorine atoms into organic molecules has revolutionized various industries, from pharmaceuticals and agrochemicals to advanced materials. Fluorinated aromatic compounds, in particular, exhibit unique electronic, thermal, and biological properties. Ethyl 3-amino-4-fluorobenzoate (CAS 455-75-4) is a notable example, serving as a versatile intermediate in sophisticated chemical syntheses. This article explores the chemistry of such compounds and guides researchers on how to efficiently source CAS 455-75-4.

Understanding Fluorinated Aromatics

Fluorine is the most electronegative element, and its introduction into organic structures profoundly impacts molecular behavior. In aromatic systems, fluorine atoms can alter electron distribution, influence reactivity, enhance metabolic stability, and modify lipophilicity. These characteristics make fluorinated aromatics highly sought after for designing molecules with specific, often superior, performance attributes.

Ethyl 3-amino-4-fluorobenzoate: Properties and Applications

Ethyl 3-amino-4-fluorobenzoate (CAS 455-75-4) is characterized by a benzene ring substituted with an amino group, a fluorine atom, and an ethyl ester. This specific arrangement of functional groups makes it a valuable synthon. The amino group can participate in nucleophilic reactions, while the fluorine atom influences the electronic properties of the ring and can increase resistance to oxidative metabolism. The ester can be readily converted into carboxylic acids, amides, or alcohols. Consequently, this intermediate finds significant use:

  • In Pharmaceutical Synthesis: As a precursor for APIs, impacting drug efficacy and metabolic profiles.
  • In Agrochemical Development: For creating advanced herbicides, insecticides, and fungicides.
  • In Materials Science: Potentially for specialty polymers or electronic materials due to its chemical structure.

Sourcing Strategies for Researchers and Buyers

For those looking to buy Ethyl 3-amino-4-fluorobenzoate, a strategic approach to sourcing is essential:

  • Quality Assurance: Prioritize suppliers who provide comprehensive analytical data, including NMR and HPLC, to confirm purity and identity.
  • Supplier Verification: Engage with reputable chemical manufacturers and distributors who have established quality control and supply chain management systems.
  • Price Inquiry: Obtain quotes from multiple sources, paying close attention to price per unit and potential bulk discounts from manufacturers.
  • Technical Support: Seek suppliers who can offer technical information and support regarding the product's use and handling.

Your Trusted Source for Intermediates

As a dedicated chemical manufacturer, we specialize in providing high-quality intermediates like Ethyl 3-amino-4-fluorobenzoate (CAS 455-75-4). We are committed to delivering products that meet stringent industry standards, backed by robust quality control and responsive customer service. We invite researchers and procurement specialists to contact us for detailed product specifications, pricing, and to discuss your specific requirements for this vital fluorinated aromatic intermediate.