At NINGBO INNO PHARMCHEM CO.,LTD., we believe in providing a comprehensive understanding of the chemicals we supply. Glycerol Formal (GF), a compound increasingly recognized for its versatility, warrants a closer look at its chemistry, properties, and synthesis.

Glycerol Formal is essentially a cyclic acetal formed from the reaction between glycerol and formaldehyde. Chemically, it exists as a mixture of isomers, predominantly 5-hydroxymethyl-1,3-dioxolane and 4-hydroxymethyl-1,3-dioxolane. Its molecular formula is C₄H₈O₃, with a molecular weight of approximately 104.11 g/mol. At room temperature, it presents as a clear, colorless, and viscous liquid. This physical state, coupled with its unique chemical structure, dictates many of its valuable applications.

The synthesis of Glycerol Formal typically involves an acid-catalyzed condensation reaction between glycerol and formaldehyde. This process requires careful control of reaction conditions to ensure high yield and purity, minimizing residual reactants or byproducts. The resulting compound exhibits good chemical stability, making it suitable for use in formulations that may undergo various processing conditions or require a long shelf life.

Key properties that make Glycerol Formal highly sought after include its miscibility with water and a wide range of organic solvents. This amphiphilic nature allows it to act as an effective cosolvent, capable of dissolving both polar and non-polar compounds. Its relatively low vapor pressure and high boiling point also contribute to its safety and handling ease in industrial settings.

The unique combination of these glycerol formal properties and applications makes it an indispensable component in fields ranging from pharmaceuticals and veterinary medicine to cosmetics and industrial chemicals. Understanding the fundamental chemistry behind Glycerol Formal is key to appreciating its broad utility and the value it brings to various product formulations. For any inquiries about buy glycerol formal pharmaceutical grade or its industrial uses, NINGBO INNO PHARMCHEM CO.,LTD. is your trusted partner.