Lurasidone, an atypical antipsychotic medication, has proven effective in treating conditions like schizophrenia and bipolar depression. Its complex molecular structure is achieved through a multi-step chemical synthesis, where specific intermediates play pivotal roles. Among these, (3aR,4S,7R,7aS) 4,7-Methano-1H-isoindole-1,3(2H)-dione, identified by CAS 14805-29-9, is a cornerstone intermediate, integral to constructing the drug's core scaffold.

The synthesis pathway for Lurasidone typically involves sophisticated organic chemistry techniques. CAS 14805-29-9, with its rigid bicyclic framework, provides a precise stereochemical foundation required for the subsequent elaboration of the Lurasidone molecule. Researchers and chemical manufacturers often seek this intermediate from reliable sources to ensure the integrity of their synthetic routes. High purity, generally above 99.0%, is a critical attribute, as even minor impurities can lead to side reactions, reduced yields, or difficulties in the purification of the final Active Pharmaceutical Ingredient (API).

Manufacturers specializing in pharmaceutical intermediates, particularly in regions like China, are key suppliers of CAS 14805-29-9. These producers focus on optimized synthetic methods to achieve the required purity and stereochemical configuration. For example, a common synthesis route involves the hydrogenation of a precursor, followed by isolation and purification of the desired intermediate. The quality control measures applied during these processes are extensive, often including techniques like HPLC, GC, and NMR spectroscopy.

The availability and pricing of this intermediate are directly linked to the efficiency of its manufacturing process and the demand for Lurasidone. Pharmaceutical companies looking to buy CAS 14805-29-9 for their production or R&D needs should prioritize suppliers who can guarantee batch-to-batch consistency and provide robust technical support. Understanding the chemical characteristics and synthesis role of this intermediate empowers buyers to make informed decisions and secure a stable supply chain.

In summary, (3aR,4S,7R,7aS) 4,7-Methano-1H-isoindole-1,3(2H)-dione (CAS 14805-29-9) is more than just a chemical compound; it is a critical component that enables the efficient and reliable production of Lurasidone. By focusing on sourcing this intermediate from quality-assured manufacturers, the pharmaceutical industry can continue to deliver this essential medication to patients worldwide.