The development of targeted cancer therapies has revolutionized oncology. Olaparib, a potent PARP inhibitor, represents a significant breakthrough in treating specific genetic mutations that drive cancer growth. Understanding the chemical journey from raw materials to the final active pharmaceutical ingredient (API) provides valuable insight into the complexity and precision required in pharmaceutical manufacturing.

At the heart of Olaparib’s synthesis lies a series of carefully selected chemical intermediates. One of the most critical is 2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic Acid, identified by its CAS number 763114-26-7. This compound, with its molecular formula C16H11FN2O3, serves as a foundational building block, contributing key structural elements to the final Olaparib molecule.

The chemical properties of this intermediate, typically a white to off-white powder with high purity, are crucial. High purity ensures that side reactions are minimized and that the final API meets stringent pharmaceutical quality standards. The specific arrangement of fluorine, nitrogen, and oxygen atoms within its structure, combined with the phthalazinone and benzoic acid moieties, makes it uniquely suited for its role in the synthetic pathway.

For researchers and chemical engineers, sourcing reliable intermediates like CAS 763114-26-7 is paramount. When looking to purchase or obtain a quote for this compound, it's important to partner with a reputable manufacturer or supplier. These partners must demonstrate a commitment to quality control and provide comprehensive technical documentation, such as CoA and MSDS.

The journey of synthesizing complex molecules like Olaparib highlights the importance of specialized chemical intermediates. By understanding the role and sourcing of compounds like 2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic Acid, the pharmaceutical industry can continue to develop and deliver innovative treatments. Ensuring a stable supply from trusted sources, particularly from leading chemical providers in regions like China, is key to advancing pharmaceutical manufacturing.