For researchers and laboratory professionals, a fundamental understanding of the chemical compounds they use is crucial for experimental success. PIPES Monosodium Salt, identified by CAS number 10010-67-0, is a chemical entity with specific properties that lend themselves to critical roles in both biological buffering and as a valuable intermediate in chemical synthesis. This article aims to shed light on the chemistry of PIPES Monosodium Salt for R&D scientists, including its key attributes and how to source it effectively.

Chemical Structure and Properties of PIPES Monosodium Salt

PIPES Monosodium Salt, chemically known as sodium 2-[4-(2-sulfoethyl)piperazin-1-yl]ethane-1-sulfonate, possesses a unique molecular structure that dictates its functionality. The presence of the piperazine ring, a six-membered ring containing two nitrogen atoms, is a common motif in many biologically active molecules and pharmaceutical intermediates. Coupled with the sulfonic acid groups (which exist as sulfonate salts in the monosodium form), this structure contributes to its solubility and buffering capacity. The sulfonic acid groups impart a strong acidic character, while the amine nitrogens in the piperazine ring can also participate in acid-base reactions. Its molecular formula is C8H17N2NaO6S2, with a molecular weight of approximately 324.34 g/mol.

Applications in Biological Buffering and Synthesis

As a biological buffer, PIPES is particularly effective in the pH range of 6.5 to 7.5. It exhibits minimal interaction with metal ions and has low UV absorbance, making it suitable for spectrophotometric assays. Its zwitterionic nature contributes to its buffering efficiency. Beyond its buffering capabilities, PIPES Monosodium Salt serves as a valuable intermediate in organic synthesis. Its structure can be modified or incorporated into larger molecules, finding use in the development of new pharmaceuticals or specialty chemicals. For R&D scientists, securing a reliable supply of this compound, often characterized by its white powder appearance and high purity (≥99%), is key to reproducible research.

Sourcing Strategies for R&D Professionals

Researchers looking to buy PIPES Monosodium Salt often seek high-purity grades from dependable suppliers. China offers a competitive landscape for chemical sourcing, with numerous manufacturers capable of producing PIPES Monosodium Salt to exacting standards. When sourcing, R&D professionals should:

  • Verify Specifications: Always confirm the CAS number (10010-67-0) and purity (e.g., 99%) align with your project's requirements.
  • Request Technical Documentation: Obtain a Certificate of Analysis (CoA) for quality assurance.
  • Compare Suppliers: Research manufacturers and suppliers for competitive pricing and reliable delivery.
  • Understand Packaging: Confirm the packaging is suitable for laboratory use and storage.

By focusing on these aspects, R&D scientists can efficiently acquire PIPES Monosodium Salt from trusted China-based manufacturers, ensuring the quality and consistency needed for their advanced research projects.