For organic chemists and pharmaceutical formulators, understanding the precise chemical characteristics of intermediates is fundamental to successful synthesis. (S)-N-Boc-γ-Iodo-Abu-OtBu, bearing the CAS number 161370-66-7, stands out as a particularly versatile and valuable molecule in this regard. Its unique structural features make it a cornerstone for building complex organic molecules, especially within the pharmaceutical industry.

Decoding the Structure: Why It Matters

(S)-N-Boc-γ-Iodo-Abu-OtBu is a protected amino acid derivative. The 'Boc' group is a widely used protecting group for amines, offering stability during various chemical transformations and allowing for selective deprotection when needed. The presence of an iodine atom at the gamma position makes this molecule highly reactive in nucleophilic substitution and transition-metal catalyzed cross-coupling reactions, such as Suzuki, Heck, and Sonogashira couplings. These reactions are instrumental in forming carbon-carbon bonds, a critical step in constructing complex organic skeletons found in many drugs. The 'S' stereochemistry further indicates its utility in synthesizing enantiomerically pure compounds, a requirement for many modern pharmaceuticals.

Applications in API Synthesis

The pharmaceutical industry relies heavily on chiral intermediates like (S)-N-Boc-γ-Iodo-Abu-OtBu for the efficient synthesis of Active Pharmaceutical Ingredients (APIs). Its ability to introduce specific chiral centers and functional groups precisely makes it indispensable for developing targeted therapies. Researchers often seek out this compound to create novel drug candidates or to optimize existing synthesis routes, aiming for higher yields and purities. When you need to buy this intermediate, ensuring it comes from a reputable manufacturer with a high purity standard (e.g., 97% Min.) is crucial for the success of these demanding applications.

Sourcing the Right Intermediate

For scientists and procurement specialists, identifying reliable suppliers for (S)-N-Boc-γ-Iodo-Abu-OtBu is a key task. The availability of this intermediate from manufacturers in China provides a valuable option for global sourcing, often at competitive prices. Looking for suppliers that offer detailed technical data, consistent quality, and flexible packaging options (from milligrams for R&D to kilograms for production) is advisable. Companies that provide prompt quotes and efficient worldwide delivery are preferred partners for any pharmaceutical R&D or manufacturing operation. We specialize in providing such critical chemical intermediates, ensuring you have the materials needed to drive your research forward.