Benzyl Carbamate, scientifically known as Carbamic acid benzyl ester and bearing the CAS number 621-84-1, is a valuable organic compound with a molecular formula of C8H9NO2. Its structure features a carbamate functional group attached to a benzyl moiety, contributing to its unique chemical properties and reactivity. This compound typically appears as an off-white to light beige powder, with a melting point generally ranging from 86-89 °C, indicating its solid state at room temperature.

The synthesis of Benzyl Carbamate is commonly achieved through the reaction of benzyl chloroformate with ammonia. This process involves carefully adding benzyl chloroformate to a cold ammonia solution under stirring, followed by isolation and purification of the resulting precipitate. The resulting Benzyl Carbamate is highly regarded for its purity, often exceeding 99.0% (HPLC), making it suitable for demanding applications in fine chemical synthesis.

The applications of Benzyl Carbamate are broad and significant. In organic synthesis, it is primarily employed as a protecting group for amine functionalities. The benzyloxycarbonyl (Cbz) group derived from Benzyl Carbamate offers stability during various chemical reactions and can be selectively removed under specific conditions, such as catalytic hydrogenation. This characteristic makes it an indispensable tool in multi-step synthesis, particularly in the fields of peptide synthesis and the development of pharmaceutical intermediates. For researchers and manufacturers, understanding these chemical principles is key to leveraging Benzyl Carbamate effectively.

Beyond its role as a protecting group, Benzyl Carbamate also finds use as a key intermediate in the production of various pharmaceutical compounds and is sometimes utilized as an internal standard for quantitative analysis in biological samples. Companies seeking to purchase Benzyl Carbamate for their research and development or manufacturing needs can find reliable suppliers by focusing on purity, consistent quality, and competitive pricing, with many international buyers turning to manufacturers in China for their supply requirements.