The Chemistry of Butyryl Chloride: Synthesis, Reactivity, and Industrial Significance
Butyryl chloride, bearing the CAS number 141-75-3 and chemical formula C4H7ClO, is a crucial organic compound that commands significant attention within the chemical industry. As an acyl chloride, it is characterized by a carbonyl group bonded to a chlorine atom, endowing it with exceptional reactivity. This inherent reactivity makes it an invaluable intermediate in a multitude of chemical synthesis processes, particularly in the production of pharmaceuticals, agrochemicals, and other specialized organic chemicals.
The chemical structure of Butyryl chloride, CH3CH2CH2COCl, dictates its behavior. It is a colorless liquid with a pungent odor, and it reacts vigorously with protic solvents like water and alcohols. This reaction with water, known as hydrolysis, yields butyric acid and hydrogen chloride gas, highlighting the need for careful handling and storage under anhydrous conditions. The reactions with alcohols lead to the formation of esters, and with amines, they produce amides, both of which are classes of compounds with extensive industrial applications.
The industrial significance of Butyryl chloride is deeply rooted in its role as a synthetic precursor. In the pharmaceutical sector, it is indispensable for the synthesis of a wide array of Active Pharmaceutical Ingredients (APIs). Researchers and manufacturers rely on its ability to introduce the butyryl moiety, which can be instrumental in tailoring the pharmacological properties of drug molecules. For example, it can be used in the synthesis of certain anesthetic agents, sedatives, or anti-inflammatory compounds. The demand for high-purity Butyryl chloride (often specified as 99% min assay) is therefore critical to ensure the quality and safety of pharmaceutical products.
Similarly, the agrochemical industry utilizes Butyryl chloride extensively in the creation of pesticides, herbicides, and fungicides. These crop protection agents are vital for ensuring global food security by safeguarding crops from pests and diseases. The specific chemical structures that confer biological activity in these agrochemicals are often assembled using Butyryl chloride as a key building block. Manufacturers in this sector often seek direct suppliers for bulk purchases to manage costs and ensure supply chain stability.
Beyond these primary applications, Butyryl chloride finds use in general organic synthesis, contributing to the development of new materials, flavors, and fragrances. Its predictable reactivity makes it a favored reagent in both academic research and industrial R&D environments.
For organizations seeking to procure Butyryl chloride, partnering with reliable manufacturers is essential. Companies like NINGBO INNO PHARMCHEM CO.,LTD. specialize in producing high-quality Butyryl chloride, offering it at competitive prices directly from their manufacturing facilities in China. When inquiring about purchasing Butyryl chloride, specifying the CAS number (141-75-3) and desired purity level is crucial for obtaining accurate quotations and ensuring that the product meets the required technical specifications. The availability of comprehensive technical documentation, such as Safety Data Sheets (SDS) and Certificates of Analysis (CoA), from the supplier further solidifies a trustworthy partnership.
In essence, the chemistry of Butyryl chloride, characterized by its potent reactivity and versatility, underpins critical manufacturing processes across key global industries. Its continued importance in synthesis highlights the enduring value of reliable chemical intermediates.
Perspectives & Insights
Agile Reader One
“In the pharmaceutical sector, it is indispensable for the synthesis of a wide array of Active Pharmaceutical Ingredients (APIs).”
Logic Vision Labs
“Researchers and manufacturers rely on its ability to introduce the butyryl moiety, which can be instrumental in tailoring the pharmacological properties of drug molecules.”
Molecule Origin 88
“For example, it can be used in the synthesis of certain anesthetic agents, sedatives, or anti-inflammatory compounds.”