The development of potent antibacterial agents is a cornerstone of modern medicine, and the efficacy of many powerful antibiotics is significantly enhanced by co-administration with specific inhibitors. Cilastatin is one such critical inhibitor, working in tandem with antibiotics like Imipenem to prevent their rapid metabolism in the kidneys, thereby maximizing their systemic availability and antibacterial impact. At the heart of Cilastatin synthesis lies a crucial chiral intermediate: (S)-(+)-2,2-Dimethylcyclopropane Carboxamide, identified by CAS number 75885-58-4.

The chemistry involved in producing Cilastatin relies heavily on the specific structure and high purity of its precursors. (S)-(+)-2,2-Dimethylcyclopropane Carboxamide serves as a foundational chiral building block. Its cyclopropane ring system and the specific stereochemistry at the chiral center are essential for the subsequent synthetic steps that build the complex structure of Cilastatin. When researchers and manufacturers seek to buy (S)-(+)-2,2-Dimethylcyclopropane Carboxamide, they are looking for a material that provides precise stereochemical control, a quality often guaranteed by reputable suppliers with high chiral content specifications (≥99.0%).

The synthesis pathway from (S)-(+)-2,2-Dimethylcyclopropane Carboxamide to Cilastatin involves several carefully controlled chemical reactions. While the exact proprietary routes may vary, the core transformation utilizes the carboxamide functional group and the chiral cyclopropane moiety. Sourcing this intermediate from a reliable CAS 75885-58-4 supplier ensures that the foundational chemistry proceeds with the desired purity and stereochemical integrity. For instance, understanding the competitive Cilastatin intermediate price from manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. allows for better project budgeting and cost management in the complex drug development process.

The pharmaceutical industry’s demand for enantiomerically pure compounds underscores the importance of intermediates like (S)-(+)-2,2-Dimethylcyclopropane Carboxamide. The presence of the correct enantiomer is critical for the pharmacological activity and safety profile of the final drug. Therefore, selecting a quality-focused (S)-(+)-2,2-Dimethylcyclopropane Carboxamide manufacturer that rigorously tests for chiral purity is non-negotiable. This intermediate’s consistent availability and adherence to strict quality standards are vital for ensuring the efficacy of treatments against serious bacterial infections.

In essence, the synthesis of Cilastatin is a testament to the power of precise organic chemistry, with (S)-(+)-2,2-Dimethylcyclopropane Carboxamide playing an irreplaceable role. For any pharmaceutical company involved in the production or research of Cilastatin-based therapies, securing a dependable supply of this key intermediate is paramount. We encourage you to contact us to explore purchasing options and learn more about the quality and reliability we offer as your trusted (S)-(+)-2,2-Dimethylcyclopropane Carboxamide supplier.