Clevidipine is a fast-acting intravenous dihydropyridine calcium channel blocker, vital for managing hypertensive emergencies and perioperative hypertension. Its effective synthesis relies on a series of precise chemical reactions, with specific intermediates playing crucial roles in building the final molecule. Understanding these intermediates is key for chemists and formulators working in pharmaceutical research and development.

A pivotal intermediate in the Clevidipine synthesis pathway is the pyridine derivative with CAS No. 123853-39-4, known chemically as 4-(2,3-Dichlorophenyl)-1,4-dihydropyridine-3-carboxylic acid monomethyl ester. This compound serves as a foundational building block, contributing the core dihydropyridine ring structure with the essential dichlorophenyl substituent. Its consistent availability and high purity are paramount for ensuring the successful and efficient production of Clevidipine and its prodrug, Clevidipine Butyrate.

The chemical literature often highlights the complexity of synthesizing such molecules, emphasizing the need for high-quality starting materials. As a manufacturer and supplier of this critical intermediate, we are committed to providing a product that meets the stringent requirements of the pharmaceutical industry. Our off-white crystalline powder form, with a purity of u226598%, is precisely what formulators and researchers need to advance their projects. We make it easy to buy this essential chemical, offering competitive pricing and reliable delivery from our facilities in China.

For those involved in drug discovery and API manufacturing, securing a dependable supply of this intermediate is a strategic advantage. Whether you are exploring novel formulations or optimizing existing synthetic routes, our product can be a valuable asset. We encourage you to reach out to us for a detailed product inquiry, to request a sample, or to get a quote for bulk purchases. Partnering with us means securing a vital component for your pharmaceutical synthesis needs.