The Chemistry of D-3-(3-Thienyl)-alanine: Properties and Synthesis Insights
Understanding the fundamental chemistry of compounds like D-3-(3-Thienyl)-alanine is essential for leveraging their full potential in synthesis and research. This unnatural amino acid, identified by CAS 152612-26-5, possesses a unique molecular structure that combines chirality with a thiophene ring, offering distinct chemical reactivity and properties.
The molecular formula for D-3-(3-Thienyl)-alanine is C7H9NO2S, with a molecular weight of approximately 171.22 g/mol. Its defining features are the D-configuration at the alpha-carbon and the presence of a 3-thienyl group attached to the beta-carbon. This thienyl moiety, a five-membered aromatic ring containing sulfur, contributes to the molecule's electronic character and can participate in a variety of chemical reactions, including electrophilic aromatic substitution and metal-catalyzed cross-coupling reactions.
Chemists often seek D-3-(3-Thienyl)-alanine for its utility in stereoselective synthesis. The D-chirality is critical for applications where precise spatial arrangement of atoms is necessary, such as in the design of chiral drugs or catalysts. The compound typically appears as a white to off-white solid or powder, with purity levels generally around 97-98%.
While specific proprietary synthesis routes vary, the preparation of such non-proteinogenic amino acids often involves asymmetric synthesis techniques or enzymatic resolutions to achieve the desired enantiomeric purity. The availability of this compound from manufacturers in China, like NINGBO INNO PHARMCHEM CO.,LTD., signifies the advanced capabilities in producing complex chiral molecules.
For researchers and companies looking to buy D-3-(3-Thienyl)-alanine, a thorough understanding of its chemical properties and potential synthesis pathways aids in optimizing its application in their projects, whether in peptide synthesis, drug discovery, or material science.
The molecular formula for D-3-(3-Thienyl)-alanine is C7H9NO2S, with a molecular weight of approximately 171.22 g/mol. Its defining features are the D-configuration at the alpha-carbon and the presence of a 3-thienyl group attached to the beta-carbon. This thienyl moiety, a five-membered aromatic ring containing sulfur, contributes to the molecule's electronic character and can participate in a variety of chemical reactions, including electrophilic aromatic substitution and metal-catalyzed cross-coupling reactions.
Chemists often seek D-3-(3-Thienyl)-alanine for its utility in stereoselective synthesis. The D-chirality is critical for applications where precise spatial arrangement of atoms is necessary, such as in the design of chiral drugs or catalysts. The compound typically appears as a white to off-white solid or powder, with purity levels generally around 97-98%.
While specific proprietary synthesis routes vary, the preparation of such non-proteinogenic amino acids often involves asymmetric synthesis techniques or enzymatic resolutions to achieve the desired enantiomeric purity. The availability of this compound from manufacturers in China, like NINGBO INNO PHARMCHEM CO.,LTD., signifies the advanced capabilities in producing complex chiral molecules.
For researchers and companies looking to buy D-3-(3-Thienyl)-alanine, a thorough understanding of its chemical properties and potential synthesis pathways aids in optimizing its application in their projects, whether in peptide synthesis, drug discovery, or material science.
Perspectives & Insights
Nano Explorer 01
“The molecular formula for D-3-(3-Thienyl)-alanine is C7H9NO2S, with a molecular weight of approximately 171.”
Data Catalyst One
“Its defining features are the D-configuration at the alpha-carbon and the presence of a 3-thienyl group attached to the beta-carbon.”
Chem Thinker Labs
“This thienyl moiety, a five-membered aromatic ring containing sulfur, contributes to the molecule's electronic character and can participate in a variety of chemical reactions, including electrophilic aromatic substitution and metal-catalyzed cross-coupling reactions.”