For professionals in organic synthesis and pharmaceutical development, a deep understanding of the chemical properties and synthesis routes of key intermediates is fundamental. Ethyl 2-oxo-4-phenylbutyrate (CAS 64920-29-2) is a compound that merits close examination due to its critical role in producing advanced pharmaceuticals. As a versatile alpha-ketoester, its synthesis and subsequent transformations are central to many drug manufacturing processes.

The synthesis of Ethyl 2-oxo-4-phenylbutyrate typically involves established organic chemistry techniques. For instance, one common method described in literature involves the reaction of a diester with a strong base, such as potassium tert-butoxide, in an organic solvent like toluene. The subsequent work-up and purification, often through flash chromatography, yield the desired product, usually as a yellow oily liquid. This process highlights the compound's accessibility for production by specialized chemical manufacturers.

Beyond its synthesis, the true value of Ethyl 2-oxo-4-phenylbutyrate lies in its applications. It serves as a vital precursor for chiral alcohols, such as ethyl (R)-2-hydroxy-4-phenylbutyrate, which are indispensable building blocks for ACE inhibitors. This connection to cardiovascular drugs makes reliable sourcing of high-purity Ethyl 2-oxo-4-phenylbutyrate essential. When you buy Ethyl 2-oxo-4-phenylbutyrate, you are investing in a crucial component for creating medications that improve patient health.

As a leading pharmaceutical intermediate manufacturer, we are committed to optimizing the synthesis and supply of this compound. We understand the need for strict quality control to ensure high purity and minimal byproducts, which is critical for sensitive pharmaceutical applications. Sourcing from a reputable Ethyl 2-oxo-4-phenylbutyrate supplier in China ensures that you receive a product that meets stringent industry standards, facilitating your research and production without compromising on quality or price.

Exploring the chemistry behind Ethyl 2-oxo-4-phenylbutyrate reveals its importance in stereoselective synthesis. Its use in asymmetric reduction reactions and enantioselective hydrogenation further emphasizes its versatility in creating optically pure compounds. For R&D scientists and procurement specialists looking to purchase CAS 64920-29-2, partnering with a knowledgeable manufacturer provides access to valuable technical insights and a consistent supply chain. Trust our expertise as a premier manufacturer to support your chemical synthesis needs.