The intricate world of organic synthesis relies on a toolkit of versatile chemical intermediates that enable the construction of complex molecular architectures. Among these, ethyl 2-oxopropanoate, scientifically known as Propanoic acid, 2-oxo-, ethyl ester and identified by CAS number 617-35-6, stands out for its unique reactivity and broad applicability, particularly within the pharmaceutical and fine chemical industries. As a leading manufacturer and supplier of this essential compound from China, we are keen to highlight its chemical nuances and significant applications.

Chemical Properties and Reactivity

Ethyl 2-oxopropanoate is a colorless, transparent liquid with a molecular formula of C5H8O3 and a molecular weight of approximately 116.115 g/mol. Its structure features both a ketone carbonyl group and an ester moiety, which are central to its synthetic utility. The alpha-keto ester functionality allows it to undergo a variety of reactions, including:

  • Nucleophilic Addition: The carbonyl group is susceptible to nucleophilic attack, enabling the introduction of various substituents.
  • Condensation Reactions: It readily participates in condensation reactions, such as Knoevenagel or Claisen condensations, forming new carbon-carbon bonds.
  • Cyclization Reactions: This intermediate is frequently used in the synthesis of heterocyclic compounds, which are common motifs in pharmaceutical agents.
  • Ester Chemistry: The ester group can also be modified through hydrolysis, transesterification, or reduction.

Our commitment is to supply this chemical with a high purity of 99%, ensuring that its reactive potential is realized efficiently and predictably in your synthetic endeavors. If you are seeking to buy this compound for your laboratory or industrial needs, its predictable chemical behavior is a significant advantage.

Key Synthetic Applications

The diverse reactivity profile of ethyl 2-oxopropanoate makes it an invaluable component in many synthetic pathways:

  • Pharmaceutical Synthesis: It is a key intermediate in the synthesis of numerous APIs and drug candidates, contributing to the development of treatments for various diseases. Its predictable behavior in multi-step syntheses is highly valued.
  • Fine Chemical Manufacturing: Beyond pharmaceuticals, it serves as a precursor for specialty chemicals, flavors, and fragrances, demonstrating its broad industrial relevance.
  • Research and Development: In both academic and industrial research settings, it is used to explore novel reaction mechanisms and to create new molecular entities with desired properties.

As a dedicated manufacturer and supplier, we ensure that our customers have access to this vital chemical with consistent quality and reliable delivery. When you choose to buy ethyl 2-oxopropanoate from us, you are investing in a critical component for your research and production. We are here to provide the high-purity chemical intermediates necessary to drive your innovation forward.