For procurement professionals and R&D scientists in the chemical and pharmaceutical industries, a deep understanding of product specifications is crucial. N-Fmoc-L-glutamic acid alpha-benzyl ester (CAS 122350-52-1), often abbreviated as Fmoc-Glu-OBzl, is a specialty chemical where precise details matter significantly. This article aims to provide essential chemical information to help you make informed purchasing decisions when you decide to buy this vital compound.

At its core, Fmoc-Glu-OBzl is an unnatural amino acid derivative. Its molecular formula is C27H25NO6, with a molecular weight of approximately 459.49 g/mol. The compound typically presents as a white or off-white crystalline powder, a characteristic that buyers should confirm with their potential supplier. Its melting point usually falls within the range of 110-120°C, and its optical activity, often measured as specific rotation, is typically around -16.0 ± 3° at a given concentration and solvent (e.g., C=1 in MeOH). These parameters are key indicators of purity and stereochemical integrity.

The assay of N-Fmoc-L-glutamic acid alpha-benzyl ester is a critical specification. Most reputable manufacturers, especially those serving the pharmaceutical sector, will guarantee an assay of ≥98%. This high purity is essential for its primary use in peptide synthesis, where even minor impurities can lead to unwanted side reactions, reduced yields, and compromised final product quality. When comparing price, always cross-reference it with the guaranteed assay and other essential specifications.

For bulk purchasers, understanding the storage and handling requirements is also important. Typically, Fmoc-Glu-OBzl should be stored in a cool place, with the container kept tightly closed in a dry and well-ventilated area to maintain its stability and prevent degradation. As a trusted manufacturer, we ensure that our product adheres to these quality standards and provide comprehensive technical data sheets upon request.

When you are ready to secure your supply of this critical intermediate, consider a manufacturer that prioritizes quality control and offers competitive pricing. Ensuring you have all the necessary chemical details at hand will facilitate a smoother procurement process and guarantee the efficacy of Fmoc-Glu-OBzl in your research and production applications.