For research and development scientists engaged in complex organic synthesis, particularly in the realm of peptide chemistry, understanding the nuances of key reagents is critical. HATU (CAS 148893-10-1) has emerged as a powerful tool, widely adopted for its exceptional capabilities as a peptide coupling reagent. Its molecular structure and reactivity profile make it an invaluable asset in laboratories focused on innovation and discovery.

HATU, chemically known as O-(7-Azabenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate, belongs to the guanidinium class of coupling reagents. Its efficacy stems from its ability to rapidly activate carboxyl groups, forming reactive esters that readily undergo amide bond formation with amines. This process is fundamental to the synthesis of peptides, which are chains of amino acids linked by amide bonds. R&D scientists often choose to buy HATU when tackling challenging coupling reactions, such as those involving sterically hindered amino acids or sequences prone to racemization. The reagent's design helps to suppress these side reactions, leading to cleaner products and higher yields.

The detailed chemical properties of HATU, including its molecular formula (C10H15F6N6OP) and weight (380.23 g/mol), are important for researchers planning precise synthetic strategies. Its appearance as a white crystalline powder, often with a purity exceeding 99%, underscores its suitability for sensitive applications. When scientists research where to purchase HATU, they are looking for suppliers who can guarantee this high level of purity and provide comprehensive product documentation, such as Certificates of Analysis (CoA).

The applications of HATU extend beyond basic peptide synthesis. It is instrumental in the creation of peptide libraries, the development of novel peptide-based therapeutics, and in the modification of biomolecules. For laboratories aiming to synthesize complex peptide structures or create custom peptide fragments, procuring HATU from a reliable manufacturer is a key step. We serve as a dedicated supplier of high-purity HATU in China, committed to supporting the vital research conducted by scientists worldwide. We encourage R&D professionals to reach out for pricing and bulk order inquiries.

In conclusion, HATU is a sophisticated and highly effective reagent for peptide synthesis. Its chemical efficiency, low epimerization, and high purity make it an indispensable tool for R&D scientists. By understanding its chemical properties and securing a reliable supply from a trusted manufacturer, researchers can maximize their success in creating complex peptide structures for various scientific applications.