The pharmaceutical industry is a complex ecosystem where the synthesis of active pharmaceutical ingredients (APIs) relies on a chain of meticulously produced chemical intermediates. Among these, 2-Hydroxypyridine (CAS 142-08-5) holds a significant position, particularly in the production of the widely used antiepileptic drug, Levetiracetam.

Levetiracetam, known for its effectiveness in managing partial seizures, epilepsy, and myoclonic seizures, is synthesized through various chemical pathways. A common and important route involves 2-Hydroxypyridine as a key starting material or intermediate. The chemical structure of 2-Hydroxypyridine, with its pyridine ring and hydroxyl group, provides the necessary functional groups and reactivity for subsequent transformations to form the final Levetiracetam molecule.

For R&D scientists and procurement professionals, sourcing reliable, high-purity 2-Hydroxypyridine is essential. The quality of this intermediate directly influences the efficiency of the synthesis, the purity of the resulting Levetiracetam, and ultimately, the safety and efficacy of the medication. Typical specifications include a purity level of ≥99% and a low moisture content, usually ≤0.5%. The physical appearance is generally an off-white to light yellow powder.

When initiating the search for this chemical, industry professionals often use specific search queries such as “2-Hydroxypyridine supplier,” “buy 2-hydroxypyridine,” or “2-pyridone manufacturer.” These searches aim to identify reliable sources that can provide the material consistently and at a competitive price. Many pharmaceutical companies look to established manufacturers in regions like China that have robust chemical synthesis capabilities.

The consistent availability of high-quality 2-Hydroxypyridine from trusted suppliers is critical for maintaining the production pipeline of Levetiracetam. For those in the market to purchase this vital intermediate, ensuring that the supplier adheres to strict quality control measures and can provide the necessary documentation is key to a successful and compliant manufacturing process.