For research and development scientists in the pharmaceutical and fine chemical industries, a deep understanding of chemical compounds is fundamental. Methyl 6-fluoro-1H-indole-4-carboxylate (CAS: 1082040-43-4) is one such compound that warrants attention due to its critical role as an intermediate. Its molecular structure, properties, and reactivity make it an indispensable component in the synthesis of complex molecules, most notably Rucaparib, an anti-cancer therapeutic.

The chemical name, Methyl 6-fluoro-1H-indole-4-carboxylate, reveals key aspects of its structure: an indole ring system, a fluorine atom at the 6th position, and a methyl ester group attached to the 4th carbon of the indole ring. The indole scaffold is a ubiquitous motif in many biologically active compounds, and the addition of a fluorine atom can significantly alter its electronic properties and metabolic stability, often enhancing its therapeutic potential. The methyl carboxylate group provides a functional handle for further chemical transformations, making it an ideal building block for multi-step syntheses.

As a manufacturer, we ensure that our Methyl 6-fluoro-1H-indole-4-carboxylate is synthesized with meticulous care, resulting in a high-purity product (≥98.0% HPLC) presented as a white to yellow powder. This level of purity is critical for R&D scientists aiming for reproducible and reliable results in their experiments. Understanding these chemical properties helps researchers plan their synthetic routes effectively. For instance, the reactivity of the ester group or potential reactions on the indole ring can be leveraged to construct more complex molecular architectures.

The primary application driving demand for this compound is its use as an intermediate in the synthesis of Rucaparib. However, its utility extends to other areas of medicinal chemistry and fine chemical synthesis where the fluorinated indole motif is desirable. Researchers looking to buy this compound for their work can rely on us as a knowledgeable supplier. We provide essential information to support your research, including detailed specifications and application insights. For those seeking to source this material, our competitive price reflects our efficient manufacturing processes.

In essence, Methyl 6-fluoro-1H-indole-4-carboxylate is a testament to the importance of specialized chemical intermediates in modern scientific advancement. As a dedicated manufacturer and supplier, we are committed to providing the chemical community with high-quality materials that fuel innovation. We invite R&D scientists to explore our offerings and discover how our product can contribute to their synthetic successes.