The Chemistry of N-BOC-O-Benzyl-L-Serine: Synthesis and Applications
Understanding the chemical properties and synthesis pathways of key intermediates is fundamental to successful chemical research and development. N-BOC-O-Benzyl-L-Serine (CAS 23680-31-1) is a prime example of such an intermediate, widely utilized in peptide synthesis and other specialized chemical processes. NINGBO INNO PHARMCHEM CO.,LTD., as a dedicated manufacturer, provides insights into the chemistry that makes this compound so valuable.
The synthesis of N-BOC-O-Benzyl-L-Serine typically involves the selective protection of L-serine. First, the alpha-amino group is protected with the tert-butyloxycarbonyl (Boc) group, commonly through reaction with di-tert-butyl dicarbonate. Subsequently, the hydroxyl group on the side chain is protected with a benzyl ether, often via reaction with benzyl bromide under basic conditions. This strategic introduction of protecting groups results in an O-benzyl-L-serine protecting group monomer that is stable under a range of reaction conditions but can be selectively cleaved when needed. NINGBO INNO PHARMCHEM CO.,LTD. employs optimized synthesis routes to ensure the high purity and consistent quality of our N-BOC-O-Benzyl-L-Serine.
The applications of N-BOC-O-Benzyl-L-Serine are diverse, stemming from its utility as a protected amino acid. Its primary use is in solid-phase and solution-phase peptide synthesis, where it serves as a building block for creating peptides with specific sequences and functionalities. The benzyl group on the serine side chain is particularly useful as it can be removed by catalytic hydrogenation, a mild deprotection method compatible with many other functional groups. This makes it an excellent choice for researchers looking to buy N-BOC-O-Benzyl-L-Serine for complex peptide assembly.
Beyond peptide synthesis, this compound finds applications in medicinal chemistry for the synthesis of drug candidates, in bioconjugation for creating targeted therapies, and in protein engineering for modifying protein structures. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing this versatile chemical intermediate to support a broad spectrum of scientific advancements. Trust NINGBO INNO PHARMCHEM CO.,LTD. for your supply of high-quality N-BOC-O-Benzyl-L-Serine and explore the full potential of its chemistry.
The synthesis of N-BOC-O-Benzyl-L-Serine typically involves the selective protection of L-serine. First, the alpha-amino group is protected with the tert-butyloxycarbonyl (Boc) group, commonly through reaction with di-tert-butyl dicarbonate. Subsequently, the hydroxyl group on the side chain is protected with a benzyl ether, often via reaction with benzyl bromide under basic conditions. This strategic introduction of protecting groups results in an O-benzyl-L-serine protecting group monomer that is stable under a range of reaction conditions but can be selectively cleaved when needed. NINGBO INNO PHARMCHEM CO.,LTD. employs optimized synthesis routes to ensure the high purity and consistent quality of our N-BOC-O-Benzyl-L-Serine.
The applications of N-BOC-O-Benzyl-L-Serine are diverse, stemming from its utility as a protected amino acid. Its primary use is in solid-phase and solution-phase peptide synthesis, where it serves as a building block for creating peptides with specific sequences and functionalities. The benzyl group on the serine side chain is particularly useful as it can be removed by catalytic hydrogenation, a mild deprotection method compatible with many other functional groups. This makes it an excellent choice for researchers looking to buy N-BOC-O-Benzyl-L-Serine for complex peptide assembly.
Beyond peptide synthesis, this compound finds applications in medicinal chemistry for the synthesis of drug candidates, in bioconjugation for creating targeted therapies, and in protein engineering for modifying protein structures. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing this versatile chemical intermediate to support a broad spectrum of scientific advancements. Trust NINGBO INNO PHARMCHEM CO.,LTD. for your supply of high-quality N-BOC-O-Benzyl-L-Serine and explore the full potential of its chemistry.
Perspectives & Insights
Bio Analyst 88
“employs optimized synthesis routes to ensure the high purity and consistent quality of our N-BOC-O-Benzyl-L-Serine.”
Nano Seeker Pro
“The applications of N-BOC-O-Benzyl-L-Serine are diverse, stemming from its utility as a protected amino acid.”
Data Reader 7
“Its primary use is in solid-phase and solution-phase peptide synthesis, where it serves as a building block for creating peptides with specific sequences and functionalities.”