The Chemistry of N-Cbz-L-serine: Properties and Synthesis Applications
Understanding the fundamental chemistry of key synthesis components is vital for any researcher or product formulator. N-Cbz-L-serine, identified by CAS number 1145-80-8, is a derivative of the amino acid serine that offers unique properties making it invaluable in organic and peptide synthesis. This article delves into its chemical characteristics and diverse applications.
N-Cbz-L-serine possesses the molecular formula C11H13NO5 and a molecular weight of approximately 239.22 g/mol. As a white to cream-colored powder, it typically exhibits a melting point in the range of 115-120°C. The presence of the carbobenzyloxy (Cbz) protecting group on the alpha-amino group renders it stable under various reaction conditions commonly employed in peptide synthesis, while the primary alcohol in the side chain (the hydroxy group) remains available for further chemical modification. Its solubility profile typically includes good solubility in DMSO and sparing solubility in acetic acid, which are common solvents in chemical synthesis.
The primary utility of N-Cbz-L-serine lies in its role as a protected amino acid building block. In peptide synthesis, it allows for the sequential addition of amino acids to form peptide chains without unwanted side reactions. The Cbz group can be selectively removed under specific conditions, typically hydrogenolysis, to reveal the free amine for subsequent coupling steps. Beyond peptide synthesis, its structural features make it a valuable intermediate for the synthesis of various pharmaceutical compounds and other complex organic molecules.
For professionals seeking to buy N-Cbz-L-serine, understanding these chemical properties helps in selecting the right supplier and ensuring product suitability for their specific applications. Partnering with a reputable manufacturer that provides detailed technical data, such as spectral information and purity assays, is essential. As a leading chemical manufacturer, we provide high-quality N-Cbz-L-serine, ensuring purity and consistency that supports your advanced synthesis needs, whether for R&D or large-scale production.
Perspectives & Insights
Alpha Spark Labs
“As a leading chemical manufacturer, we provide high-quality N-Cbz-L-serine, ensuring purity and consistency that supports your advanced synthesis needs, whether for R&D or large-scale production.”
Future Pioneer 88
“Understanding the fundamental chemistry of key synthesis components is vital for any researcher or product formulator.”
Core Explorer Pro
“N-Cbz-L-serine, identified by CAS number 1145-80-8, is a derivative of the amino acid serine that offers unique properties making it invaluable in organic and peptide synthesis.”