The Chemistry of Niclosamide (CAS 50-65-7): Properties and Industrial Uses
Niclosamide, identified by CAS number 50-65-7, is a chemical compound with a fascinating chemical structure and a wide range of industrial applications. Primarily known for its potent biological activities, it is commonly supplied as a yellow crystalline powder. Understanding its chemical properties is key to appreciating its utility in sectors such as pharmaceuticals, veterinary medicine, and pest control. As a dedicated manufacturer and supplier of fine chemicals, our expertise in producing high-purity Niclosamide powder ensures its effectiveness and reliability for diverse industrial needs.
Chemically, Niclosamide belongs to the salicylanilide class, characterized by its molecular formula C13H8Cl2N2O4 and a molecular weight of approximately 327.12 g/mol. Its structure features chlorinated phenyl rings and a hydroxyl group, contributing to its specific biological interactions. The compound's solubility is noteworthy; it is soluble in organic solvents like ethanol and DMSO but generally insoluble in water, a property that influences its formulation and application methods. Its melting point is typically in the range of 225-233 °C, indicating its solid, crystalline nature at room temperature.
The industrial applications of Niclosamide are primarily driven by its biological activity. As an anthelmintic, it is highly effective against tapeworm infections, making it a staple in veterinary medicine for treating livestock and poultry. Its high purity, often exceeding 99%, is crucial for efficacy and safety in these formulations. Furthermore, Niclosamide serves as an essential molluscicide, utilized in public health programs to control snail populations that transmit schistosomiasis. This broad spectrum of activity also extends to its use as a pharmaceutical intermediate, where it serves as a building block for synthesizing other medicinal compounds.
Recent research has also highlighted Niclosamide's potential in cancer treatment, investigating its ability to inhibit key cellular pathways. This expanding application profile underscores the compound's versatility and importance. For industries seeking to source Niclosamide, partnering with a reliable manufacturer that guarantees purity and consistency is vital. Our production facility in China adheres to strict quality control standards, ensuring that our clients receive top-grade Niclosamide powder. We are committed to providing comprehensive support, from detailed product specifications to efficient global logistics, making us a preferred supplier for businesses worldwide looking to buy Niclosamide.
Perspectives & Insights
Silicon Analyst 88
“Its structure features chlorinated phenyl rings and a hydroxyl group, contributing to its specific biological interactions.”
Quantum Seeker Pro
“The compound's solubility is noteworthy; it is soluble in organic solvents like ethanol and DMSO but generally insoluble in water, a property that influences its formulation and application methods.”
Bio Reader 7
“Its melting point is typically in the range of 225-233 °C, indicating its solid, crystalline nature at room temperature.”