Understanding the chemical nuances of intermediates is key for any scientist or formulator. 1-Ethynyl-3-fluorobenzene, identified by CAS number 2561-17-3, is a compound that offers a fascinating study in organic chemistry, with significant implications for synthesis in various industries. As a specialized supplier, we are dedicated to providing high-quality materials that meet the rigorous demands of modern research and industrial production.

At its core, 1-Ethynyl-3-fluorobenzene is an aromatic organic compound. Its structure features a benzene ring substituted with an ethynyl (-C≡CH) group and a fluorine atom at the meta position. This unique combination grants it distinct reactivity patterns. The ethynyl group is a versatile functional handle, readily participating in a host of addition and coupling reactions, such as Sonogashira coupling, click chemistry (copper-catalyzed azide-alkyne cycloaddition), and various cyclization reactions. The fluorine atom, known for its electronegativity and small size, can influence the electronic properties of the molecule, affect its metabolic stability in biological systems, and modify its lipophilicity. This makes 1-Ethynyl-3-fluorobenzene a valuable building block, especially in pharmaceutical and agrochemical synthesis, where fine-tuning these properties is often essential for efficacy.

The synthesis of 1-Ethynyl-3-fluorobenzene typically involves reactions that introduce or modify the ethynyl group on a fluorinated benzene precursor. Common methods include palladium-catalyzed cross-coupling reactions or the dehydrohalogenation of appropriate vinyl halides. While specific synthetic routes can vary based on starting materials and desired purity, the compound is widely available from reliable chemical manufacturers. For researchers looking to buy this compound, it is readily accessible in various purities, with high-purity grades (e.g., ≥98%) being preferred for sensitive applications to ensure predictable reaction outcomes and minimize the formation of unwanted by-products.

The applications of 1-Ethynyl-3-fluorobenzene are diverse, ranging from its role as a key intermediate in the synthesis of pharmaceuticals and agrochemicals to its use in the creation of advanced materials like conductive polymers and liquid crystals. Its molecular structure provides a foundation for building complex molecules with tailored properties. We offer this compound with a commitment to quality and consistency, providing competitive prices for bulk orders. If your research or production requires this critical intermediate, we invite you to request a quote and experience our reliable service.

By understanding the synthetic accessibility and reactivity of 1-Ethynyl-3-fluorobenzene, chemists can effectively leverage its potential to drive innovation across multiple scientific disciplines.