For chemists and materials scientists, understanding the chemical intricacies of building blocks is fundamental to unlocking their full potential. 2-Amino-5-bromo-3-methylpyridine (CAS 3430-21-5) is a prime example of such a compound, valued for its reactivity and the diverse transformations it enables. NINGBO INNO PHARMCHEM CO.,LTD., a leading manufacturer and supplier of fine chemicals, offers this compound and insights into its chemical behavior.

Chemical Profile of 2-Amino-5-bromo-3-methylpyridine

This compound, with the molecular formula C6H7BrN2 and a molecular weight of 187.04 g/mol, features a pyridine core functionalized with an amino group at position 2, a bromine atom at position 5, and a methyl group at position 3. Its physical properties include an appearance ranging from off-white to brown crystalline powder and a melting point between 88-95°C. These characteristics are critical for handling and processing. The bromine atom is a key site for various palladium-catalyzed cross-coupling reactions, while the amino group can undergo derivatization or participate in nucleophilic reactions.

Key Chemical Transformations and Applications

The versatility of 2-Amino-5-bromo-3-methylpyridine stems from its capacity to undergo several important chemical reactions:

  • Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki-Miyaura, Heck, and Sonogashira couplings, allowing the introduction of aryl, alkenyl, and alkynyl groups, respectively. These reactions are pivotal in constructing complex organic molecules.
  • Nucleophilic Substitution: The amino group can be acylated, alkylated, or involved in other reactions, while the bromine can be replaced by various nucleophiles under appropriate conditions.
  • Derivatization: It serves as a precursor for synthesizing advanced pharmaceutical intermediates and agrochemical active ingredients, leveraging its inherent reactivity.

These transformations are frequently utilized in the synthesis of novel drugs and advanced materials. When you buy this intermediate, you are investing in a platform for diverse chemical innovation.

Sourcing Quality Intermediates: A Smart Choice

As a dedicated supplier of CAS 3430-21-5, NINGBO INNO PHARMCHEM CO.,LTD. ensures that our product meets stringent quality standards, with an assay purity of ≥98.0%. This commitment guarantees that your synthetic endeavors will benefit from consistent reactivity and reliable outcomes. We offer competitive pricing and dependable supply, making us an ideal partner for your chemical needs.

Researchers and formulators are encouraged to inquire about the technical details and to request a quote for purchasing 2-Amino-5-bromo-3-methylpyridine. Secure your supply from a trusted China manufacturer.

Contact NINGBO INNO PHARMCHEM CO.,LTD. today to learn more about the chemical potential of 2-Amino-5-bromo-3-methylpyridine and how we can support your projects.