In the realm of organic synthesis, the identification and utilization of versatile building blocks are fundamental to innovation. 4-(Hydroxymethyl)phenylacetic acid (CAS: 73401-74-8) stands out as a compound of significant interest due to its unique structural features and reactivity. This white powder, often supplied with high purity, serves as a crucial intermediate for numerous chemical transformations.

The molecular structure of 4-(Hydroxymethyl)phenylacetic acid incorporates both a primary alcohol (hydroxymethyl group) and a carboxylic acid group, attached to a phenyl ring. This bifunctionality allows it to participate in a wide array of chemical reactions. The carboxylic acid group can undergo esterification, amidation, and salt formation, while the hydroxymethyl group can be oxidized, esterified, or converted into halides. This dual reactivity is what makes it an excellent choice for complex multi-step syntheses, supporting the development of novel chemical entities. Researchers often seek to buy this compound to explore its capabilities in various synthetic strategies, benefiting from its consistent quality as provided by a reputable manufacturer like NINGBO INNO PHARMCHEM CO.,LTD.


The synthesis of 4-(Hydroxymethyl)phenylacetic acid is typically achieved through well-established organic chemistry methodologies. A common pathway involves the hydrolysis of a suitable precursor, such as 4-bromomethylphenylacetic acid, under basic conditions. Optimization of reaction parameters, including temperature, solvent, and reagent stoichiometry, is crucial for achieving high yields and purity, which directly impacts its price and suitability for demanding applications. Understanding these synthesis routes allows chemists to efficiently produce this valuable reagent.


The applications stemming from its versatility are broad. It is frequently employed in the synthesis of specialty chemicals, agrochemicals, and importantly, as a key intermediate in the pharmaceutical industry for analgesics and anti-inflammatory agents. Its contribution to creating compounds with specific biological activities underscores its importance. For those in the scientific community looking to source this essential compound, NINGBO INNO PHARMCHEM CO.,LTD. provides a dependable supply, ensuring your organic synthesis projects proceed smoothly.