In the realm of organic chemistry, specific molecular structures serve as indispensable building blocks for the creation of more complex and functional compounds. 6-(Trifluoromethyl)pyridine-3-carbonitrile, with its unique combination of a pyridine ring, a trifluoromethyl group, and a nitrile moiety, stands out as a highly versatile intermediate. Understanding its intrinsic properties and diverse applications is key for chemists aiming to synthesize novel molecules. NINGBO INNO PHARMCHEM CO.,LTD. provides this compound, ensuring high purity for all your synthetic endeavors.

Let's explore the defining characteristics of 6-(trifluoromethyl)pyridine-3-carbonitrile. Its molecular formula, C7H3F3N2, and a molecular weight of approximately 172.107 g/mol, hint at its compact yet functional structure. Physically, it presents as a yellow solid, a form that is convenient for handling and storage. The melting point range of 37-41°C further solidifies its status as a stable solid under typical laboratory conditions. While the provided information does not include a boiling point, its flash point of 180°F suggests moderate flammability, requiring standard precautions during handling.

The significance of this molecule lies not only in its physical form but more importantly in its chemical reactivity. The trifluoromethyl group (–CF3) is electron-withdrawing, influencing the electron density distribution across the pyridine ring. This can impact the reactivity of the ring itself, making it amenable to specific types of electrophilic or nucleophilic substitutions. Concurrently, the nitrile group (–CN) is a highly versatile functional group. It can undergo hydrolysis to form carboxylic acids, reduction to primary amines, or participate in [3+2] cycloaddition reactions to form heterocycles like tetrazoles, which are prevalent in medicinal chemistry.

These chemical properties make 6-(trifluoromethyl)pyridine-3-carbonitrile an invaluable intermediate in various fields. For pharmaceutical research, it serves as a scaffold for building molecules with potential therapeutic activity. The trifluoromethyl group can enhance bioavailability and binding affinity, while the pyridine core offers points for further functionalization to target specific biological pathways. Similarly, in the agrochemical industry, this intermediate can be used to synthesize new generations of pesticides and herbicides, where the trifluoromethyl moiety often contributes to increased potency and stability in environmental conditions.

When considering where to buy such a specialized intermediate, it is crucial to partner with a reliable supplier. NINGBO INNO PHARMCHEM CO.,LTD. offers 6-(trifluoromethyl)pyridine-3-carbonitrile with a guaranteed purity of ≥98.0%. This commitment to quality ensures that your synthetic outcomes are predictable and reproducible. As a leading manufacturer in China, we provide competitive prices for both small-scale research quantities and larger bulk purchases. We understand the importance of a consistent supply chain for our clients, whether they are conducting early-stage R&D or scaling up production.

In summary, 6-(trifluoromethyl)pyridine-3-carbonitrile is a compound of significant chemical interest and practical utility. Its physical and chemical properties make it an ideal intermediate for advanced organic synthesis in pharmaceuticals, agrochemicals, and beyond. We invite you to get a quote from NINGBO INNO PHARMCHEM CO.,LTD. to secure a high-quality supply of this essential building block.