The advent of transition metal-catalyzed cross-coupling reactions has revolutionized organic synthesis, providing chemists with powerful tools to construct complex molecular architectures. Among these, the Suzuki-Miyaura coupling stands out for its broad substrate scope, functional group tolerance, and mild reaction conditions. This reaction's success hinges on the availability of robust and reactive organoboron reagents, such as boronate esters, exemplified by Phenoxyphenyl-4-boronic acid pinacol ester (CAS 269410-26-6).

Phenoxyphenyl-4-boronic acid pinacol ester is a fine chemical characterized by its molecular formula C18H21BO3 and a molecular weight of 296.17. Its structure combines a stable dioxaborolane ring with a phenoxyphenyl group, making it an ideal substrate for palladium-catalyzed transformations. The pinacol ester moiety confers greater stability and often better solubility in organic solvents compared to the free boronic acid, simplifying handling and reaction setup. Typical purity levels, as provided by manufacturers like us, are 99%, ensuring high efficiency in coupling reactions.

The synthesis of Phenoxyphenyl-4-boronic acid pinacol ester typically involves the lithiation of 4-bromodiphenyl ether followed by reaction with a borate ester, such as triisopropyl borate, and subsequent esterification with pinacol. This process, when executed by experienced chemical manufacturers, yields a product suitable for demanding applications. The utility of this compound extends to its role as a key intermediate in the synthesis of pharmaceuticals, agrochemicals, and advanced materials. Its phenoxyphenyl group can introduce specific electronic and steric properties into target molecules, which is critical for drug design and for tuning the performance of materials like OLEDs.

For businesses looking to buy this versatile intermediate, understanding its chemical properties and applications is crucial. Whether you are involved in drug discovery, materials science, or specialized chemical synthesis, having a reliable supplier for high-purity boronate esters is essential. We are a leading manufacturer in China, offering Phenoxyphenyl-4-boronic acid pinacol ester for your research and industrial needs. We pride ourselves on providing quality products and efficient service. If you wish to buy this compound or inquire about its price and availability, please reach out to our sales team.

Our expertise in producing advanced organic intermediates ensures that our clients receive materials that meet rigorous quality standards. We support researchers and industries by providing the fundamental chemical components that drive innovation forward. Contact us for your needs in boronate esters and other fine chemicals.