The Chemistry of Ethyl 2-(1-Imidazolyl)acetate: Properties and Synthetic Utility
Ethyl 2-(1-Imidazolyl)acetate, identified by its CAS number 17450-34-9, is a fascinating organic compound that plays a crucial role in various chemical synthesis processes, particularly within the pharmaceutical industry. Understanding its chemical and physical properties is key to unlocking its full potential as a versatile intermediate.
With a molecular formula of C7H10N2O2 and a molecular weight of 154.16600, this compound is characterized by an imidazole ring attached to an ethyl acetate group. The presence of the imidazole heterocycle imparts specific electronic and steric properties that are highly valuable in organic synthesis. The compound typically presents as a white solid, with a melting point in the range of 124-125°C. Its density is approximately 1.14 g/cm³, and it has a boiling point of 293°C at 760 mmHg, indicating good thermal stability under normal reaction conditions.
The synthetic utility of Ethyl 2-(1-Imidazolyl)acetate lies in its ability to undergo a variety of chemical transformations. The nitrogen atoms within the imidazole ring can participate in nucleophilic reactions, while the ester group can be modified through hydrolysis, transesterification, or reduction. This makes it an ideal precursor for the synthesis of more complex imidazole-containing compounds, which are frequently found in biologically active molecules. For instance, its use as a pharmaceutical intermediate involves incorporating the imidazole moiety into drug candidates, influencing their pharmacokinetic and pharmacodynamic properties.
When considering the purchase of this chemical, factors like purity are critical. A minimum purity of 97% is generally sought after, ensuring reliable and reproducible results in your synthetic endeavors. Storage conditions are also important; typically, it should be sealed tightly and protected from light, with long-term storage recommended in a freezer to maintain its integrity. Researchers often search for reliable suppliers to buy Ethyl 2-(1-Imidazolyl)acetate, ensuring they receive a product that meets these specifications.
As a key component in the toolbox of organic chemists, Ethyl 2-(1-Imidazolyl)acetate enables the efficient construction of novel molecular frameworks. Its availability from manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. facilitates research and development, supporting the ongoing quest for new therapeutic agents and advanced materials.
With a molecular formula of C7H10N2O2 and a molecular weight of 154.16600, this compound is characterized by an imidazole ring attached to an ethyl acetate group. The presence of the imidazole heterocycle imparts specific electronic and steric properties that are highly valuable in organic synthesis. The compound typically presents as a white solid, with a melting point in the range of 124-125°C. Its density is approximately 1.14 g/cm³, and it has a boiling point of 293°C at 760 mmHg, indicating good thermal stability under normal reaction conditions.
The synthetic utility of Ethyl 2-(1-Imidazolyl)acetate lies in its ability to undergo a variety of chemical transformations. The nitrogen atoms within the imidazole ring can participate in nucleophilic reactions, while the ester group can be modified through hydrolysis, transesterification, or reduction. This makes it an ideal precursor for the synthesis of more complex imidazole-containing compounds, which are frequently found in biologically active molecules. For instance, its use as a pharmaceutical intermediate involves incorporating the imidazole moiety into drug candidates, influencing their pharmacokinetic and pharmacodynamic properties.
When considering the purchase of this chemical, factors like purity are critical. A minimum purity of 97% is generally sought after, ensuring reliable and reproducible results in your synthetic endeavors. Storage conditions are also important; typically, it should be sealed tightly and protected from light, with long-term storage recommended in a freezer to maintain its integrity. Researchers often search for reliable suppliers to buy Ethyl 2-(1-Imidazolyl)acetate, ensuring they receive a product that meets these specifications.
As a key component in the toolbox of organic chemists, Ethyl 2-(1-Imidazolyl)acetate enables the efficient construction of novel molecular frameworks. Its availability from manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. facilitates research and development, supporting the ongoing quest for new therapeutic agents and advanced materials.
Perspectives & Insights
Future Origin 2025
“The synthetic utility of Ethyl 2-(1-Imidazolyl)acetate lies in its ability to undergo a variety of chemical transformations.”
Core Analyst 01
“The nitrogen atoms within the imidazole ring can participate in nucleophilic reactions, while the ester group can be modified through hydrolysis, transesterification, or reduction.”
Silicon Seeker One
“This makes it an ideal precursor for the synthesis of more complex imidazole-containing compounds, which are frequently found in biologically active molecules.”