The Chemistry of L-Threonine Benzyl Ester HCl: Synthesis & Purity Explained
Understanding the chemical intricacies of pharmaceutical intermediates is vital for anyone involved in synthesis and formulation. L-Threonine Benzyl Ester Hydrochloride (CAS: 33645-24-8), often abbreviated as H-Thr-OBzl·HCl, is a prominent example of such a compound, highly valued for its role in peptide synthesis and as a versatile chiral building block in organic chemistry. For professionals seeking to buy L-Threonine Benzyl Ester Hydrochloride, clarity on its synthesis and purity is essential.
The production of L-Threonine Benzyl Ester Hydrochloride typically involves the esterification of L-threonine with benzyl alcohol, followed by hydrochloride salt formation. This process requires careful control of reaction conditions to maintain the stereochemical integrity of threonine and to achieve high purity. The benzyl ester serves as a robust protecting group for the carboxyl terminus, which is critical for sequential amino acid addition in peptide synthesis without undesirable side reactions. A reputable pharmaceutical intermediate manufacturer will employ advanced purification techniques, such as recrystallization and chromatography, to ensure that the final product meets stringent specifications, commonly ≥98.0% purity as determined by High-Performance Liquid Chromatography (HPLC).
As a leading supplier in China, we are committed to delivering intermediates that exceed expectations. The physical and chemical properties of our L-Threonine Benzyl Ester Hydrochloride, such as its white crystalline powder appearance and a defined melting point range (128.0 to 132.0 °C), are meticulously documented. These characteristics are critical indicators of quality for researchers and formulators. Ensuring a stable supply of such high-purity materials is our priority, supporting clients in their quest for novel drug development and complex chemical synthesis projects.
When evaluating the price of this essential intermediate, consider the investment in quality control and the expertise required for its synthesis. We provide comprehensive technical support and welcome inquiries for samples and quotes, enabling you to assess the suitability of our L-Threonine Benzyl Ester Hydrochloride for your specific applications. Partnering with a reliable manufacturer ensures that your synthetic pathways are built on a foundation of chemical excellence.
Perspectives & Insights
Agile Reader One
“L-Threonine Benzyl Ester Hydrochloride (CAS: 33645-24-8), often abbreviated as H-Thr-OBzl·HCl, is a prominent example of such a compound, highly valued for its role in peptide synthesis and as a versatile chiral building block in organic chemistry.”
Logic Vision Labs
“For professionals seeking to buy L-Threonine Benzyl Ester Hydrochloride, clarity on its synthesis and purity is essential.”
Molecule Origin 88
“The production of L-Threonine Benzyl Ester Hydrochloride typically involves the esterification of L-threonine with benzyl alcohol, followed by hydrochloride salt formation.”