Phenyl Dichlorophosphate (CAS 770-12-7) is an organophosphorus compound that holds significant importance in various chemical industries due to its unique chemical structure and reactivity. As a key intermediate, understanding its properties and how it is synthesized is crucial for chemists and engineers looking to leverage its potential. This article explores the fundamental chemistry of Phenyl Dichlorophosphate, offering insights valuable for anyone looking to buy or utilize this compound effectively.

At its core, Phenyl Dichlorophosphate is characterized by the presence of a phenyl group attached to a phosphoryl dichloride moiety (C6H5OPOCl2). This structure imbues it with notable reactivity, particularly the two highly reactive chlorine atoms and the phenolic oxygen group. Typically appearing as a colorless to pale yellow corrosive liquid at room temperature, it is sensitive to moisture, readily undergoing hydrolysis to release hydrogen chloride gas. This inherent reactivity makes it an exceptional phosphorylating agent and dehydrating agent in organic synthesis. For those seeking to optimize their synthetic routes, understanding this reactivity is key to unlocking the compound's full potential. When considering price and availability, reliable manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. are essential sources.

The synthesis of Phenyl Dichlorophosphate commonly involves the reaction of phenol with phosphorus oxychloride (POCl3). A typical industrial process might involve adding phenol dropwise to phosphorus oxychloride under controlled temperature conditions, often in the presence of a catalyst. Following the reaction, excess phosphorus oxychloride is distilled off, and the product is further purified through vacuum distillation. This meticulous process ensures the high purity (often ≥99%) required for its demanding applications, such as in the pharmaceutical sector. The efficiency and yield of this synthesis are critical factors for suppliers to manage, ensuring a consistent and cost-effective supply for bulk purchases.

The diverse applications of Phenyl Dichlorophosphate stem directly from its chemical properties. It is indispensable in the phosphorylation of nucleotides, amino acids, and alcohols, playing a vital role in the creation of complex organic molecules. Its utility extends to being a precursor for pesticides, flame retardants, and vital drug intermediates. For researchers and industrial chemists, sourcing this compound from a reputable manufacturer ensures access to a reagent that can drive innovation and efficiency in their respective fields. The ability to obtain expert guidance from a trusted supplier in China can also prove invaluable for navigating its hazardous nature and optimizing its use.