In the realm of fine chemicals and organic synthesis, understanding the properties and applications of key intermediates is vital for successful project outcomes. (R)-(-)-O-Formylmandeloyl Chloride, identified by CAS number 29169-64-0, is a compound of significant interest due to its chiral nature and reactive acyl chloride functionality. As a premier supplier and manufacturer in China, we aim to provide comprehensive insights into this valuable chemical, assisting researchers and procurement specialists in making informed decisions. Whether you're looking to buy it for R&D or larger-scale production, knowing its characteristics is key.

Key Chemical Properties and Reactivity

(R)-(-)-O-Formylmandeloyl Chloride is characterized by its clear, colorless to light yellow liquid appearance. Its molecular formula is C9H7ClO3, with a molecular weight of 198.6 g/mol. The compound exhibits a boiling point of 221 °C and a density of 1.290 g/mL at 20 °C. The presence of the formyloxy group and the highly reactive acid chloride group makes it a versatile reagent. The acid chloride moiety readily undergoes nucleophilic substitution reactions with alcohols, amines, and other nucleophiles to form esters, amides, and other derivatives. This reactivity is central to its utility in creating more complex organic molecules.

Synthesis and Sourcing from China

The synthesis of (R)-(-)-O-Formylmandeloyl Chloride typically involves the conversion of the corresponding chiral acid using chlorinating agents such as thionyl chloride. Maintaining stereochemical integrity during synthesis is a critical aspect, which experienced manufacturers excel at. When sourcing from China, it's important to engage with suppliers who can guarantee product purity and accurate specifications. We offer this compound with high purity, ensuring it meets the demanding requirements of pharmaceutical and specialty chemical synthesis. Our competitive pricing makes it an accessible option for researchers and businesses alike.

Diverse Applications in Synthesis

  • Chiral Building Block: Its defined stereochemistry makes it ideal for synthesizing enantiomerically pure compounds used in pharmaceuticals and fine chemicals.
  • Acylating Agent: Efficiently introduces the formyl-mandeloyl group into various substrates, facilitating the construction of complex molecular architectures.
  • API Intermediate: A crucial component in the synthesis pathways of various Active Pharmaceutical Ingredients, where chirality is key to biological activity.
  • Research and Development: Valued by R&D chemists for its predictable reactivity and ability to introduce specific functionalities into novel compounds.

We are a dedicated supplier committed to providing (R)-(-)-O-Formylmandeloyl Chloride to the global market. If you are looking to purchase this important intermediate, we invite you to request a quote. Our aim is to ensure you receive a high-quality product from a trusted manufacturer, facilitating your research and production goals.