In the realm of organic synthesis, specific chiral intermediates play a pivotal role in achieving desired molecular structures with high precision. (S)-Mandelonitrile (CAS 28549-12-4), a derivative of phenylacetonitrile, stands out as a key chiral building block, sought after by researchers and manufacturers for its versatility. Understanding its chemical properties and application scope is essential for anyone involved in advanced chemical production.

Chemical Profile of (S)-Mandelonitrile

With the molecular formula C8H7NO and a molecular weight of 133.15 g/mol, (S)-Mandelonitrile presents as a white powder. Its structure features a chiral center at the carbon atom bearing the hydroxyl and nitrile groups, attached to a phenyl ring. This stereochemistry is critical, as many biologically active molecules, particularly pharmaceuticals, exhibit enantioselectivity, meaning only one enantiomer provides the desired therapeutic effect.

Key Applications in Synthesis

The primary utility of (S)-Mandelonitrile lies in its function as an intermediate in various synthetic pathways:

  • Pharmaceutical Intermediate: It is a fundamental precursor for synthesizing numerous Active Pharmaceutical Ingredients (APIs). Its chiral nature allows for the stereoselective construction of drug molecules, leading to more potent and safer medications. Procurement managers often seek this compound to ensure the efficient production of chiral drugs.
  • Fine Chemical Synthesis: Beyond pharmaceuticals, (S)-Mandelonitrile is employed in the synthesis of other fine chemicals, where specific stereochemistry is required for functionality or performance. This includes agrochemicals, specialty polymers, and complex organic molecules used in advanced materials.
  • Research and Development: For academic and industrial R&D teams, (S)-Mandelonitrile serves as a valuable reagent to explore novel synthetic routes, develop new catalysts, and investigate reaction mechanisms in chiral chemistry.

Sourcing and Supply Chain Considerations

When considering the purchase of (S)-Mandelonitrile, particularly for bulk requirements, identifying a reliable manufacturer and supplier is crucial. Companies looking to buy this intermediate often prioritize consistent quality, competitive pricing, and dependable delivery. Sourcing from China offers a competitive advantage due to the country's extensive chemical manufacturing infrastructure. As a dedicated supplier of high-purity chemical intermediates, we ensure that our (S)-Mandelonitrile meets the rigorous demands of modern chemical synthesis. We encourage R&D scientists and product formulators to inquire about our supply capabilities and explore how our consistent quality can benefit your projects.