The intricate process of pharmaceutical manufacturing relies heavily on the precise chemistry of its raw materials and intermediates. Ethyl 2-oxo-4-phenylbutyrate (CAS 64920-29-2) is a prime example of an intermediate whose chemical attributes make it indispensable for creating vital medicines. As a specialized manufacturer and supplier, we are dedicated to providing this compound with the quality and consistency that the pharmaceutical industry demands.

Ethyl 2-oxo-4-phenylbutyrate is classified as an alpha-ketoester, a class of organic compounds known for their reactivity and utility in complex synthesis. Its molecular formula, C12H14O3, and molecular weight of 206.24 g/mol define its specific chemical behavior. The compound appears as a light yellow oily liquid, with a density of approximately 1.091 g/mL at 25°C and a boiling point of around 132°C at 2 mmHg. These physical and chemical properties are crucial for chemists designing synthetic routes, ensuring efficient reactions and predictable outcomes.

The primary driver for the demand of Ethyl 2-oxo-4-phenylbutyrate is its pivotal role in the synthesis of blockbuster drugs. For instance, it is a key precursor in the production of Lisinopril, an ACE inhibitor that has revolutionized the management of hypertension and heart failure. The enantioselective synthesis of Lisinopril relies on the stereochemical information inherent or introduced via intermediates like Ethyl 2-oxo-4-phenylbutyrate. Similarly, its application in the synthesis of Cilastatin, an essential component used alongside antibiotics, further solidifies its importance in the pharmaceutical supply chain.

When considering where to buy this essential intermediate, selecting a supplier with robust quality control is paramount. Companies specializing in pharmaceutical intermediates, such as ourselves, ensure that each batch meets stringent purity requirements, often exceeding 99.0%. This high purity minimizes side reactions and impurities in the final API, which is critical for drug safety and efficacy. Moreover, reliable suppliers can offer competitive prices, especially for bulk purchases, making efficient production economically viable.

The ongoing research into optimizing the synthesis of Ethyl 2-oxo-4-phenylbutyrate and exploring its use in novel chiral transformations underscores its value. As a forward-thinking chemical manufacturer, we are committed to innovation in our production processes to meet the evolving needs of drug discovery and development. For any pharmaceutical company seeking a dependable source of this critical intermediate, engaging with experienced and quality-focused suppliers is the pathway to success.