Understanding the chemical intricacies of intermediates is fundamental for any B2B client in the pharmaceutical and fine chemical sectors. 1-Cyclopentylpiperazine (CAS: 21043-40-3) is a heterocyclic amine that plays a vital role in organic synthesis. As a leading supplier of such specialized chemicals, we aim to provide insights into its properties and synthesis, helping you make informed decisions when you consider to purchase it.

The molecular formula of 1-Cyclopentylpiperazine is C9H18N2, with a molecular weight of 154.25 g/mol. Its structure features a piperazine ring substituted with a cyclopentyl group. This unique arrangement confers specific reactivity and physical properties, such as a boiling point of approximately 48°C and a density of 0.989 g/cm³. Its appearance is typically colorless to light yellow liquid, and it exhibits a pKa of around 9.28 ± 0.10, indicating its basic nature.

The synthesis of 1-Cyclopentylpiperazine generally involves the alkylation of piperazine with a cyclopentyl halide or equivalent reagent. While specific proprietary methods exist among manufacturers, the core chemistry involves forming a new carbon-nitrogen bond. Careful control of reaction conditions, purification techniques, and analytical methods are essential to achieve the high purity (often exceeding 98%) required for its downstream applications.

The versatility of 1-Cyclopentylpiperazine as a synthon makes it invaluable in various chemical pathways. Its most notable uses are in the synthesis of pharmaceuticals, where it serves as a key building block for complex molecules like H3 receptor antagonists and estrogen receptor modulators. These applications demand a consistent and reliable supply chain, which we strive to provide as a dedicated manufacturer in China.

When evaluating a potential supplier for 1-Cyclopentylpiperazine, look for companies that can provide comprehensive technical data, including safety data sheets (SDS) and product specifications. The price of the chemical can be influenced by the synthesis route, scale of production, and purity. By working directly with manufacturers, you can often secure more competitive pricing and ensure product quality meets your exact needs.

In conclusion, the chemical properties and synthesis of 1-Cyclopentylpiperazine are key to its utility in advanced organic chemistry and pharmaceutical development. For those looking to buy this crucial intermediate, understanding these aspects and partnering with a reliable manufacturer or supplier is the first step toward successful product innovation. We are committed to being your trusted source for high-quality chemical intermediates.