In the intricate world of organic chemistry, the selection of the right starting materials and intermediates dictates the success of complex syntheses. 2-Bromo-4-methylpyridine (CAS: 4926-28-7) is a prime example of such a pivotal compound, offering a wealth of synthetic opportunities due to its chemical structure and reactivity. For researchers and chemists involved in drug discovery, agrochemical development, and material science, understanding its applications is key.

The core utility of 2-Bromo-4-methylpyridine lies in its functional groups. The pyridine ring provides a heterocyclic aromatic core, while the methyl group at the 4-position offers a site for potential functionalization. However, it is the bromine atom at the 2-position that imbues this molecule with significant synthetic versatility. This bromine atom acts as a leaving group in nucleophilic substitution reactions and is a key participant in various palladium-catalyzed cross-coupling reactions, such as Suzuki, Stille, and Sonogashira couplings.

These reactions allow chemists to efficiently introduce carbon-carbon or carbon-heteroatom bonds, thereby building more complex molecular architectures. For instance, in pharmaceutical research, this intermediate can be coupled with boronic acids or organotin compounds to create novel scaffolds for potential therapeutic agents. Its use in creating pyridinylimidazole-type kinase inhibitors, as seen in advanced medicinal chemistry research, highlights its importance in synthesizing biologically active molecules.

Beyond pharmaceuticals, 2-Bromo-4-methylpyridine finds applications in agrochemical synthesis, contributing to the development of crop protection agents. Its derivatives can be designed to exhibit specific biological activities, enhancing the efficacy of herbicides, insecticides, and fungicides. Furthermore, in material science, its structural features can be exploited to create functional polymers or advanced materials with unique properties.

As a manufacturer and supplier of this critical intermediate, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing researchers and industries with a high-quality product. We ensure that our 2-Bromo-4-methylpyridine meets stringent purity standards (≥99.0%), making it a reliable choice for demanding synthetic procedures. We understand the importance of consistent supply and competitive pricing for our clients, whether they are purchasing for laboratory research or large-scale production.

For chemists looking to purchase 2-Bromo-4-methylpyridine, consider us your trusted partner. We offer competitive pricing and robust supply chain management. Contact NINGBO INNO PHARMCHEM CO.,LTD. today to request a quote and discover how this versatile intermediate can enhance your synthetic endeavors.