For organic chemists and researchers in the pharmaceutical sector, understanding the synthesis and inherent properties of key building blocks is crucial for successful project execution. Boc-(S)-3-Amino-4-(3-methyl-phenyl)-butyric acid (CAS: 270062-93-6) is one such valuable intermediate, frequently sought after for its role in constructing complex organic molecules. This article explores its chemical characteristics and synthesis, providing insights for those looking to buy or utilize this compound.

Understanding the Molecular Structure and Properties

Boc-(S)-3-Amino-4-(3-methyl-phenyl)-butyric acid, also known by synonyms such as Boc-beta-HoPhe(3-Me)-OH, is characterized by its specific chiral center at the beta-carbon and the presence of a tert-butoxycarbonyl (Boc) protecting group on the amine. The methyl substituent on the phenyl ring adds another dimension to its structure, influencing its reactivity and physical properties. Typically appearing as a white to off-white solid, it possesses a standard purity of around 97% from reliable manufacturers. Its stability at room temperature and solubility in common organic solvents like methanol and chloroform make it convenient for laboratory use. Researchers often look for 'CAS 270062-93-6 supplier' to procure this specific isomer.

Synthetic Routes and Manufacturing Considerations

The synthesis of Boc-(S)-3-Amino-4-(3-methyl-phenyl)-butyric acid often involves multi-step processes to ensure the correct stereochemistry and functional group protection. While specific proprietary methods vary among manufacturers, general approaches may include:

  • Chiral Resolution: Synthesizing a racemic mixture and then employing chiral resolution techniques to isolate the desired (S)-enantiomer.
  • Asymmetric Synthesis: Utilizing chiral catalysts or auxiliaries to directly synthesize the (S)-enantiomer with high enantiomeric excess.
  • Boc Protection: Introducing the tert-butoxycarbonyl (Boc) group onto the amino function, typically using di-tert-butyl dicarbonate (Boc anhydride).

Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. invest heavily in process optimization to ensure high yields, purity, and cost-effectiveness when producing this compound. For those considering a 'buy Boc-(S)-3-Amino-4-(3-methyl-phenyl)-butyric acid' order, understanding the manufacturing process can build confidence in the supplier's capabilities.

Applications in Research and Development

The primary utility of Boc-(S)-3-Amino-4-(3-methyl-phenyl)-butyric acid lies in its role as a versatile intermediate:

  • Peptide Synthesis: It's a valuable building block for creating peptides with unique side chains or modified backbone structures.
  • Drug Discovery: It can be incorporated into small molecules being developed as potential drug candidates, particularly in areas where precise molecular architecture is critical.
  • Organic Synthesis: Its functional groups and chiral center make it suitable for a wide range of transformations in complex organic synthesis projects.

When you search for 'N-Boc-S-3-Amino-4-(3-methyl-phenyl)-butyric acid bulk purchase', you are often looking to leverage these synthetic advantages in larger scale projects.

In conclusion, Boc-(S)-3-Amino-4-(3-methyl-phenyl)-butyric acid is a critical chiral intermediate with well-defined chemical properties. For chemists and procurement specialists seeking this compound, identifying a reliable manufacturer and understanding its synthetic background ensures successful integration into their chemical workflows.