N-Desmethyl Imatinib (CAS 404844-02-6) is a molecule of significant interest in the pharmaceutical and chemical industries. As the primary active metabolite of the widely used anticancer drug Imatinib, its chemical structure and synthesis are of considerable importance for researchers and manufacturers alike. Understanding these aspects can help prospective buyers make informed decisions when sourcing this compound.

Chemically, N-Desmethyl Imatinib is a derivative of benzamide, featuring a complex molecular structure that includes piperazine, pyridine, and pyrimidine rings. Its molecular formula is C28H29N7O, with a molecular weight of approximately 479.58 g/mol. The absence of a methyl group on one of the nitrogen atoms in the piperazine ring distinguishes it from Imatinib. This seemingly small structural difference leads to its unique properties and biological activity as a metabolite.

The synthesis of N-Desmethyl Imatinib typically involves several complex steps, often mirroring the metabolic pathway or utilizing specialized organic synthesis techniques to build the intricate molecular framework. While the precise proprietary synthesis routes can vary among manufacturers, the general approach involves coupling various organic fragments under controlled conditions. For instance, a common strategy might involve the synthesis of intermediate building blocks, followed by carefully orchestrated coupling reactions to assemble the final molecule. Ensuring high purity in these multi-step syntheses is a testament to the expertise of the chemical manufacturer.

For those looking to buy N-Desmethyl Imatinib, particularly for use as a pharmaceutical intermediate or a research standard, understanding its synthesis sheds light on the importance of sourcing from manufacturers with advanced chemical synthesis capabilities. Companies that specialize in fine chemicals and complex organic molecules are best positioned to produce N-Desmethyl Imatinib with the required purity and consistency.

As a leading chemical supplier in China, we are dedicated to the precise synthesis and quality assurance of N-Desmethyl Imatinib. Our production processes are designed to achieve high purity levels, typically exceeding 99%, which is critical for its intended applications. We understand the chemical intricacies involved and employ rigorous quality control measures throughout the manufacturing process. If your research or production requires a reliable source of N-Desmethyl Imatinib, consider our capabilities. We offer competitive pricing for bulk quantities and are equipped to meet diverse customer needs. Contact us today to get a quote and learn more about the chemical synthesis and availability of our high-quality N-Desmethyl Imatinib.