For chemists and product formulators, a deep understanding of the chemical properties and synthesis routes of key intermediates is fundamental. 2-Amino-5-mercapto-1,3,4-thiadiazole (CAS 2349-67-9) is a heterocyclic organic compound that merits such attention due to its broad utility in various synthetic pathways.

The synthesis of 2-Amino-5-mercapto-1,3,4-thiadiazole typically involves the reaction of aminothiourea with carbon disulfide in a suitable solvent like N,N-dimethylformamide (DMF), followed by treatment with a base and subsequent acidification to precipitate the product. This method allows for controlled production, yielding a compound with a distinct molecular formula of C2H3N3S2 and a molecular weight of approximately 133.2 g/mol.

Key physical and chemical properties of this thiadiazole derivative are vital for its application. It commonly appears as a white to pale yellow or cream-colored powder. Its melting point is reported to be around 235°C with decomposition, indicating its thermal stability under normal processing conditions. While specific density and refractive index values are often estimated, its limited solubility in water but better solubility in certain organic solvents dictate handling and reaction parameters. For manufacturers, understanding these characteristics is crucial for safe storage, efficient handling, and successful integration into synthesis workflows.

Beyond its physical form, the chemical reactivity of 2-Amino-5-mercapto-1,3,4-thiadiazole, stemming from its amine and thiol functional groups, makes it a versatile building block. It readily participates in reactions essential for the creation of more complex molecules. Its role as a pharmaceutical intermediate, particularly in the synthesis of carbonic anhydrase inhibitors and compounds explored for anticonvulsant activity, highlights its therapeutic potential. Similarly, its application as a pesticide intermediate in the manufacture of herbicides underscores its importance in crop protection.

For those seeking to purchase this chemical, understanding its synthesis and properties helps in evaluating potential suppliers. A manufacturer that can consistently produce this compound with high purity (e.g., 99%) and provide detailed technical data ensures that researchers and formulators can rely on its performance. Whether you are looking to buy this intermediate for research and development or for large-scale industrial production, knowledge of its chemistry is your first step towards a successful procurement and application.