In the realm of organic chemistry and pharmaceutical manufacturing, understanding the fundamental properties of key intermediates is crucial for innovation and efficient production. Trans-4-Aminocyclohexanol, identified by its CAS number 27489-62-9, is one such compound that holds significant value due to its specific chemical characteristics and diverse applications.

Chemically, Trans-4-Aminocyclohexanol is an amino alcohol featuring a cyclohexane ring. Its defining characteristic is the 'trans' configuration, where the amino group and the hydroxyl group are positioned on opposite sides of the cyclohexane ring. This spatial arrangement dictates its behavior in chemical reactions and confers stereochemical stability, a property highly prized in advanced synthesis.

The physical form of Trans-4-Aminocyclohexanol, typically a white or off-white crystalline powder, facilitates its handling and integration into various synthetic processes. Furthermore, its high purity, often specified at 99% minimum, is critical for its use in sensitive applications, particularly within the pharmaceutical industry. This purity ensures that side reactions are minimized and that the desired product is formed with high fidelity.

One of the most prominent applications of Trans-4-Aminocyclohexanol is its role as a crucial intermediate in the synthesis of Ambroxol Hydrochloride. This well-established mucolytic drug relies on Trans-4-Aminocyclohexanol for its structural backbone. The precise 'trans' isomer is often preferred for its specific reactivity and contribution to the final drug's stereochemistry.

Beyond its direct use in established drug manufacturing, Trans-4-Aminocyclohexanol is a valuable tool in drug discovery and broader organic synthesis. Its chiral nature makes it an excellent starting material or intermediate for creating complex chiral molecules. This is particularly important in medicinal chemistry, where the development of enantiomerically pure compounds is often key to achieving desired pharmacological effects and minimizing adverse reactions. Researchers utilize it for designing selective ligands, exploring CNS pathways, and developing novel therapeutic agents.

As a leading manufacturer and supplier of this versatile intermediate, we are committed to providing high-quality Trans-4-Aminocyclohexanol (CAS 27489-62-9) to researchers and manufacturers globally. We offer reliable sourcing, consistent product quality, and competitive pricing. If you are seeking this essential chemical for your organic synthesis needs or drug development projects, we invite you to contact us for a quote and to discuss your specific requirements.