For chemists engaged in synthetic projects, understanding the properties and potential of each chemical building block is fundamental. 3-Amino-4-methoxybenzonitrile, identified by CAS number 60979-25-1, is an aromatic compound that offers a rich platform for diverse chemical transformations. Its strategic importance in various research and industrial applications makes it a key intermediate for many synthetic chemists.

Chemical Properties and Reactivity Profile

3-Amino-4-methoxybenzonitrile (C8H8N2O, MW: 148.16) is characterized by its solid form, typically appearing as a light brown to brown powder, with a melting point of 84°C. The molecule features an aniline moiety (an amine attached to a benzene ring), a methoxy ether group, and a nitrile group. This arrangement confers specific reactivity: the amine is nucleophilic and can be readily functionalized; the nitrile group is an electrophilic center that can undergo nucleophilic addition or be hydrolyzed; and the methoxy group, being electron-donating, can influence the reactivity of the aromatic ring in electrophilic aromatic substitution reactions.

Chemists looking to buy 3-Amino-4-methoxybenzonitrile often do so for its ability to participate in a wide range of reactions. For example, the amino group can undergo acylation, sulfonylation, or coupling reactions. The nitrile can be transformed into carboxylic acids, amides, or amines through hydrolysis or reduction. These versatile reaction pathways allow for the synthesis of more complex molecules, including heterocycles, pharmaceuticals, and agrochemicals.

Sourcing and Quality Considerations

When procuring 3-Amino-4-methoxybenzonitrile for laboratory research or industrial synthesis, the quality of the material is paramount. Many chemists prefer to buy from manufacturers and suppliers in China, recognizing the competitive pricing and the availability of high-purity products. Companies like NINGBO INNO PHARMCHEM CO.,LTD. are known for their commitment to quality, often supplying this intermediate with a purity of 97% or higher. This ensures that the chemical behaves predictably in reactions, minimizing side products and maximizing yields.

Procurement professionals should always request detailed Certificates of Analysis (CoA) to verify purity and identity. Understanding the typical physical characteristics and handling precautions is also essential. For example, storing it in a dark place under an inert atmosphere at room temperature is often recommended, as indicated by supplier data.

Leveraging 3-Amino-4-methoxybenzonitrile in Synthesis

The strategic use of 3-Amino-4-methoxybenzonitrile can significantly streamline synthetic routes. Its readily available functional groups allow chemists to introduce specific functionalities efficiently. Whether it's for creating novel drug candidates, developing advanced materials, or synthesizing agrochemical compounds, this intermediate provides a robust starting point. If your research requires this compound, consider reaching out to a trusted supplier to get a quote and secure your supply.

In conclusion, 3-Amino-4-methoxybenzonitrile is a valuable asset in the synthetic chemist's toolkit. By understanding its chemical properties and prioritizing sourcing from reliable manufacturers, chemists can effectively leverage this intermediate to achieve their synthetic goals.