For researchers and formulators in the pharmaceutical and biotechnology sectors, selecting the right lipid excipients is paramount. Among these, lysophospholipids like 1-Palmitoyl-sn-glycero-3-phosphocholine (P-LysoPC) play a crucial role in advanced applications such as drug delivery and cellular research. This article serves as a guide for procurement managers and R&D scientists seeking to buy this vital compound, focusing on what to look for in a reliable supplier.

Understanding 1-Palmitoyl-sn-glycero-3-phosphocholine

1-Palmitoyl-sn-glycero-3-phosphocholine, identified by CAS number 17364-16-8, is a phospholipase-mediated hydrolyzed phosphocholine. It is characterized by a saturated fatty acid tail, specifically palmitic acid (16:0). Often appearing as a white to off-white powder, its biological significance is vast, contributing to cell membrane integrity and acting as a component in pulmonary surfactant. In recent years, its potential as a biomarker for certain metabolic disorders has also garnered attention.

Key Considerations When Buying Lyso-PC

When sourcing 1-Palmitoyl-sn-glycero-3-phosphocholine, several factors are critical for ensuring successful research outcomes and product development:

  • Purity Levels: The most crucial specification is purity. For advanced applications like liposomal drug delivery or sensitive biochemical assays, a high purity level, typically exceeding 99%, is essential. Impurities can lead to unpredictable results or adverse effects in drug formulations. When you buy from a reputable manufacturer, you can expect stringent quality control that guarantees this level of purity.
  • CAS Number Verification: Always confirm the CAS number (17364-16-8) to ensure you are procuring the exact compound required. This is a standard identifier that helps avoid mix-ups and ensures product traceability.
  • Application Suitability: Consider the specific application. Is the material intended for in vitro research, preclinical studies, or GMP manufacturing? Different grades and documentation may be required. For instance, researchers in cancer therapy, particularly those exploring photodynamic therapy for glioma, will need a reliable source for high-performance lipids.
  • Supplier Reputation and Support: Partnering with an experienced manufacturer and supplier offers significant advantages. Look for suppliers who provide comprehensive technical data, certificates of analysis (CoA), and responsive customer support. A supplier with a strong track record in lipid chemistry, especially in regions like China, can ensure consistent product quality and a stable supply chain, making your purchasing process smoother.

Applications Driving Demand for P-LysoPC

The demand for high-quality 1-Palmitoyl-sn-glycero-3-phosphocholine is driven by its diverse applications:

  • Drug Delivery Systems: It plays a vital role in formulating liposomes, lipid nanoparticles (LNPs), and microbubbles for targeted drug delivery, enhancing the bioavailability and efficacy of therapeutic agents.
  • Biomedical Research: Researchers utilize it in lipidomics studies to understand cellular processes, signaling pathways, and disease mechanisms.
  • Therapeutic Development: Its role in enhancing targeted therapies, such as microbubble-mediated drug delivery and its potential in photodynamic therapies, makes it a key ingredient for novel treatments.

Procuring 1-Palmitoyl-sn-glycero-3-phosphocholine

When it comes to purchasing this critical biochemical, choosing a knowledgeable and reliable manufacturer is key. As a dedicated supplier of specialized lipids, we are committed to providing researchers and pharmaceutical companies with the highest quality 1-Palmitoyl-sn-glycero-3-phosphocholine. Our rigorous quality control processes and deep understanding of lipid chemistry ensure that you receive a product that meets your demanding specifications. If you are looking to buy this essential compound and require a dependable partner for your supply needs, we encourage you to connect with us for a quote and discuss how we can support your R&D initiatives.