For procurement professionals and R&D scientists, understanding the detailed specifications of chemical raw materials is fundamental to making informed purchasing decisions. DL-Leucine (CAS 328-39-2) is a prime example of a compound where precise specifications dictate its suitability for various demanding applications, from pharmaceuticals to specialized chemical formulations. This guide focuses on the critical parameters that B2B buyers should consider when evaluating DL-Leucine, and what differentiates a quality supplier.

The most crucial specification for DL-Leucine is its assay, which indicates the percentage of the desired compound present. For pharmaceutical intermediates and high-grade research chemicals, an assay of 98.5% to 101.0% is typically required, as stated in various product data sheets. This high level of purity ensures minimal interference in downstream synthesis processes and guarantees the reliability of experimental results. When sourcing, always check the stated assay and inquire about the analytical methods used to determine it. A reputable DL-Leucine manufacturer will provide comprehensive Certificates of Analysis (COA) detailing these figures.

Beyond the main assay, understanding impurity profiles is equally important. Key impurities to monitor for DL-Leucine include:

  • Loss on Drying (LOD): This measures the amount of volatile matter, primarily water, present in the sample. A low LOD, typically not more than 0.3%, indicates a drier, more concentrated product, which is desirable for accurate weighing and formulation.
  • Residue on Ignition (ROI): Also known as sulfated ash, this test reveals the inorganic impurity content. A low ROI, generally not exceeding 0.1%, signifies a cleaner product, critical for applications where inorganic contaminants can be detrimental.
  • Heavy Metals: For pharmaceutical and food-grade applications, stringent limits on heavy metals like Lead (Pb) and Iron (Fe) are enforced. Limits of ≤10ppm for both are common, ensuring safety and compliance with regulatory standards.
  • Chloride (Cl) and Sulfate (SO4): These anionic impurities can affect reactivity and product stability. Limits like ≤0.03% for both are often specified.
  • Ammonium (NH4): Another potential impurity that needs to be controlled, typically to ≤0.02%.
  • Arsenic (As2O3): With a strict limit usually at ≤1ppm, this ensures the absence of toxic heavy metal contamination.
  • Other Amino Acids: Techniques like Thin Layer Chromatography (TLC) are used to ensure other amino acids are not detected, especially at significant levels (e.g., not detected by TLC for spotted amounts of 50μg), which is vital for chiral purity.

When procurement managers search for 'DL-Leucine price', they should cross-reference these specifications with the cost. A significantly lower price might indicate compromises on purity or impurity control. Similarly, R&D scientists evaluating 'DL-Leucine for sale' need to ensure the product's specification sheet aligns with their experimental requirements. Partnering with a trusted DL-Leucine supplier means getting transparent documentation and consistent quality that meets these critical parameters. We, as a DL-Leucine manufacturer, are committed to providing detailed specifications and reliable products to support your success.