In the intricate world of pharmaceutical synthesis, specific chemical intermediates play pivotal roles in bringing life-changing medications to fruition. 7-Methoxy-1-naphthylacetonitrile (CAS: 138113-08-3) stands out as one such critical component, primarily known for its indispensable function in the synthesis of Agomelatine. This article delves into the chemical characteristics of this compound and its significance for pharmaceutical manufacturers looking to buy 7-Methoxy-1-naphthylacetonitrile for their Agomelatine production lines.

Chemical Profile and Significance

7-Methoxy-1-naphthylacetonitrile is an organic compound characterized by its molecular formula C13H11NO and a molecular weight of 197.23 g/mol. Its structure features a naphthalene core substituted with a methoxy group at the 7th position and an acetonitrile moiety. This precise arrangement is key to its reactivity and utility in organic synthesis. Typically appearing as a white to off-white powder, its physical properties, such as a melting point of 81-83°C, are well-documented. For R&D scientists and production chemists, understanding these attributes is crucial for optimizing reaction conditions when using this intermediate.

Applications in Pharmaceutical Manufacturing

The primary and most critical application for 7-Methoxy-1-naphthylacetonitrile is its role as a key intermediate in the synthesis of Agomelatine. Agomelatine, a melatonergic antidepressant, targets both melatonin receptors (MT1 and MT2) and serotonin 5-HT2C receptors, offering a unique therapeutic profile. The successful and efficient synthesis of Agomelatine directly depends on the quality and availability of its precursors. Therefore, sourcing high-purity 7-Methoxy-1-naphthylacetonitrile from a reliable manufacturer is a strategic imperative for pharmaceutical companies.

Sourcing High-Quality Intermediates

When seeking to purchase 7-Methoxy-1-naphthylacetonitrile, pharmaceutical professionals must prioritize suppliers who can guarantee stringent quality control and consistent batch production. As a leading supplier of pharmaceutical intermediates from China, we offer material that meets the exacting standards required for API synthesis. Our commitment to quality ensures that our 7-Methoxy-1-naphthylacetonitrile is characterized by high purity (often ≥99%), minimal impurities, and stable physical properties. We understand the importance of a robust supply chain for our clients, ensuring timely delivery and competitive 7-Methoxy-1-naphthylacetonitrile price points. By choosing us, you are partnering with a dedicated entity committed to supporting your critical synthesis needs with a reliable supply of this essential intermediate.