Fatty acid metabolism is a fundamental biological process that underpins energy production and cellular function. The intricate pathways involved are continuously being explored by scientists, and specific chemical tools are vital for this research. Teglicar (CAS 250694-07-6) stands out as a key compound due to its precise role in modulating fatty acid metabolism through the inhibition of carnitine palmitoyltransferase 1A (L-CPT1).

L-CPT1 is an enzyme that plays a pivotal role in regulating the entry of long-chain fatty acids into the mitochondrial matrix. Within the mitochondria, these fatty acids are subsequently broken down through beta-oxidation to generate ATP, the primary energy currency of the cell. This process is critical for cellular energy supply, especially during periods of fasting or increased energy demand. However, dysregulation of fatty acid metabolism is implicated in various metabolic diseases, including obesity, insulin resistance, and certain types of cancer.

Teglicar functions as a selective inhibitor of the liver isoform of L-CPT1. By binding to this enzyme, it reversibly blocks the esterification of fatty acids with carnitine, thereby impeding their transport into the mitochondria. This inhibition has significant downstream effects. It can lead to a reduction in fatty acid oxidation, prompting cells to rely more on alternative fuel sources, such as glucose. This metabolic shift is of considerable interest for researchers studying conditions like type 2 diabetes, where improving glucose utilization is a therapeutic goal. Furthermore, interfering with fatty acid oxidation can impact cancer cell proliferation, as many cancer types exhibit a heightened dependence on lipids for energy and biomass.

For researchers in biochemistry and pharmacology, acquiring high-quality Teglicar is essential for conducting reliable experiments. As a leading manufacturer and supplier of fine chemicals, we provide Teglicar (CAS 250694-07-6) with guaranteed high purity. When you buy Teglicar from us, you are investing in a crucial research reagent that can help elucidate complex metabolic pathways. Our stable supply chain and competitive pricing ensure that your research needs are met efficiently. Partner with us to access this vital tool for your fatty acid metabolism studies and explore its therapeutic potential.