Cross-coupling reactions have revolutionized organic synthesis, providing chemists with efficient and selective methods for constructing complex carbon-carbon bonds. At the heart of many such transformations lies the strategic use of dihalogenated aromatic compounds, and 4-Bromo-2-iodotoluene (CAS: 260558-15-4) is a prime example of a powerful and versatile reagent for these applications. NINGBO INNO PHARMCHEM CO.,LTD., as a dedicated manufacturer in China, is proud to supply this critical intermediate.

The advantage of 4-Bromo-2-iodotoluene in cross-coupling lies in the differing reactivity of its bromine and iodine substituents. Iodine is generally more reactive in oxidative addition steps with transition metal catalysts (like palladium) compared to bromine. This differential reactivity allows for sequential, regioselective coupling reactions. For instance, one can first perform a coupling reaction at the iodo position, leaving the bromo position available for a subsequent distinct coupling reaction. This capability is invaluable for building highly functionalized molecules with precise control over the substitution pattern, a requirement often encountered in pharmaceutical development and advanced materials research. Researchers keen to leverage this power often look to buy high-quality versions of this intermediate.

Our commitment as a supplier extends beyond merely providing the chemical. We ensure that our 4-Bromo-2-iodotoluene, with its guaranteed 97%+ purity, possesses the consistent reactivity needed for successful cross-coupling. This reliability is crucial for chemists aiming to optimize reaction conditions and achieve high yields. Understanding the price and availability is also key for long-term research or production planning.

The versatility of 4-Bromo-2-iodotoluene makes it a sought-after intermediate for synthesizing biaryls, heterocycles, and other complex organic structures that form the backbone of many active pharmaceutical ingredients (APIs) and organic electronic materials. The ability to perform sequential couplings allows for the introduction of diverse functional groups, leading to a vast library of potential end products. For companies looking to purchase this intermediate, choosing a reliable manufacturer like us ensures that their synthetic strategies can be executed effectively.

We are committed to supporting the scientific community by providing access to high-quality, reliable chemical intermediates. If your research or production involves cross-coupling reactions and you require a dependable source for 4-Bromo-2-iodotoluene, we encourage you to contact us. Discover how our consistent quality, competitive pricing, and expert support can benefit your projects and accelerate your innovation.