In the complex realm of Active Pharmaceutical Ingredient (API) synthesis, the selection and sourcing of high-quality intermediates are fundamental to the success of drug development and manufacturing. N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine, bearing the CAS number 152460-10-1, stands out as a critical intermediate widely utilized in this sector. Its unique chemical structure makes it an invaluable building block for a range of therapeutic agents.

Understanding the Significance in API Synthesis

N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine (C16H15N5, MW 277.32) is often described as a yellow solid and is sought after for its high purity, typically exceeding 98%. This purity is not merely a specification but a requirement dictated by the sensitive nature of pharmaceutical synthesis. Impurities in intermediates can lead to complications in downstream reactions, affect the final API's efficacy, and pose regulatory challenges.

As an intermediate, CAS 152460-10-1 is a precursor that undergoes further chemical transformations to yield the final API. Its specific molecular arrangement provides the necessary structural components for the targeted drug molecule. Therefore, procurement managers and R&D scientists must ensure they buy this compound from reliable sources that guarantee consistent quality and supply.

Key Considerations for Sourcing API Intermediates

When a pharmaceutical company needs to source N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine, several factors are paramount:

  • Quality and Purity: As mentioned, high purity is essential. Manufacturers must provide robust quality control data, including Certificates of Analysis (CoAs).
  • Supply Reliability: A stable and consistent supply chain is crucial to avoid disruptions in manufacturing schedules. This involves working with suppliers who have strong production capacities and logistical networks.
  • Regulatory Compliance: Suppliers should adhere to relevant industry regulations and provide necessary documentation to support the buyer's regulatory filings.
  • Technical Support: Access to technical expertise from the supplier can be invaluable for troubleshooting and optimizing synthesis processes.
  • Cost-Effectiveness: While quality is paramount, competitive pricing from a trusted manufacturer ensures the overall economic viability of the API production.

NINGBO INNO PHARMCHEM CO.,LTD. is a dedicated manufacturer and supplier of N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine (CAS 152460-10-1). We pride ourselves on meeting these critical requirements, offering high-purity intermediates sourced reliably from our facilities in China. We understand the stakes involved in API synthesis and are committed to being a trusted partner for your chemical sourcing needs.

In conclusion, the careful selection of a supplier for N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine (CAS 152460-10-1) is a strategic imperative for any organization involved in API synthesis. By prioritizing quality, reliability, and expertise, businesses can ensure the smooth and successful production of essential pharmaceuticals.