Biochemical research is a field driven by precision and the meticulous use of high-quality reagents. D-Arginine (CAS 157-06-2), a chiral variant of the amino acid arginine, is a compound of significant interest and utility within this scientific domain. Its unique properties make it an indispensable tool for researchers investigating a wide array of biological processes, from cellular signaling to metabolic pathways.

The fundamental distinction of D-arginine lies in its stereochemistry. As the D-isomer of arginine, it is not typically synthesized or utilized in the same metabolic pathways as the naturally occurring L-arginine. This difference is precisely what underpins its value in biochemical research. One of its most common applications is as a control in experiments designed to study the L-arginine/nitric oxide (NO) pathway. By including D-arginine, researchers can differentiate between NO production mediated by L-arginine and other, potentially L-arginine-independent, processes. This control is vital for elucidating complex signaling cascades and validating experimental findings.

Beyond its role as a control, D-arginine itself has been the subject of research for its own biochemical activities. Studies have explored its potential to influence various cellular functions, including its impact on enzyme activity and its interactions with specific cellular receptors. Its ability to inhibit certain enzymes, such as arginine decarboxylase, further highlights its distinct biochemical profile and potential for targeted research applications.

The use of D-arginine extends to areas such as peptide synthesis. Incorporating D-amino acids into peptides can impart unique properties, such as increased resistance to proteolysis (enzymatic breakdown) and altered conformational stability. This makes D-arginine a valuable building block for creating synthetic peptides with tailored functionalities for research purposes, including the development of novel probes or therapeutic candidates.

For researchers and procurement specialists, sourcing D-arginine requires a keen eye for quality. The compound is typically supplied as a white crystalline powder, with purity levels often specified as greater than 98% or 99%. When you are looking to buy D-arginine for your laboratory, prioritizing suppliers who offer comprehensive analytical data, such as a Certificate of Analysis (CoA), is crucial. This document should detail the purity of the D-arginine, identify any significant impurities, and confirm its identity via spectroscopic methods.

The CAS number 157-06-2 is the standard identifier for D-arginine and should be used to ensure you are ordering the correct substance. When comparing D-arginine price points, remember that quality and reliability are often more important than the lowest cost. Reputable chemical suppliers, including many in China, provide high-grade D-arginine that meets the demands of advanced biochemical research. Engaging with these suppliers, requesting quotes, and understanding their quality assurance protocols will help secure a dependable source for your research needs.