In the intricate world of pharmaceutical manufacturing, the selection and procurement of intermediates are critical steps that determine the efficiency and success of drug synthesis. D-(+)-Cellobiose (CAS 528-50-7) stands out as a vital disaccharide intermediate, valued for its specific chemical structure and versatile applications. For pharmaceutical developers and manufacturers looking to buy D-cellobiose, understanding its role and ensuring a reliable supply chain is paramount.

What is D-(+)-Cellobiose?
D-(+)-Cellobiose is a disaccharide formed by two glucose units linked via a β-(1→4) glycosidic bond. It is a reducing sugar and typically appears as a white crystalline powder. With a CAS number of 528-50-7 and a molecular formula of C12H22O11, it is characterized by its solubility in water and a melting point of around 239°C (with decomposition). Its structure makes it a key component in understanding carbohydrate chemistry and biological processes.

The Role of D-Cellobiose in Pharmaceutical Synthesis
As a pharmaceutical intermediate, D-(+)-Cellobiose serves as a fundamental building block for the synthesis of more complex molecules. Its specific glycosidic linkage and the presence of multiple hydroxyl groups make it amenable to various chemical modifications. Key applications include:

  • API Synthesis: It can be used as a starting material or intermediate in the multi-step synthesis of certain Active Pharmaceutical Ingredients (APIs), particularly those with complex carbohydrate moieties or requiring specific chiral centers.
  • Drug Delivery Systems: Derivatives of cellobiose are being explored for applications in drug delivery, such as creating biodegradable polymers or modifying existing drug molecules to improve their solubility, bioavailability, or targeting.
  • Research and Development: In the R&D phase, D-cellobiose is used to explore novel synthetic pathways and to develop new drug candidates. Its availability in high purity is essential for obtaining reliable experimental results.

Ensuring a Reliable Supply of D-Cellobiose
For pharmaceutical companies, securing a consistent and high-quality supply of D-(+)-Cellobiose (CAS 528-50-7) is crucial. Key considerations when choosing a supplier include:

  • Purity Standards: Pharmaceutical applications demand high purity, typically an assay of 98% or higher. Suppliers must provide accurate Certificates of Analysis (CoA).
  • Manufacturing Capabilities: Working with manufacturers who have robust production processes and adhere to Good Manufacturing Practices (GMP) where applicable, ensures product consistency and safety.
  • Regulatory Compliance: Understanding and adhering to international regulatory requirements for pharmaceutical intermediates is vital.
  • Competitive Pricing: Balancing quality with cost is essential for economic viability. A reliable manufacturer and supplier in China can often offer competitive pricing for bulk D-cellobiose purchases.

Conclusion
D-(+)-Cellobiose (CAS 528-50-7) is a cornerstone intermediate in pharmaceutical chemistry. Its specific structure and chemical properties make it invaluable for the synthesis of a wide range of therapeutic agents. By prioritizing purity, reliability, and cost-effectiveness in sourcing, pharmaceutical professionals can ensure the success of their critical drug development programs. If you are looking to buy D-cellobiose, we are a premier manufacturer and supplier in China, dedicated to providing the quality and service your projects demand.