D-Leucine (CAS 328-38-1): Properties and Applications in Chemical Synthesis
D-Leucine, also known as H-D-Leu-OH with CAS number 328-38-1, is a non-proteinogenic amino acid that plays a significant role in various chemical synthesis pathways, particularly in the pharmaceutical and biotechnology sectors. As a chemical intermediate, its unique chiral structure makes it invaluable for creating molecules with specific biological activities. For procurement managers and R&D scientists, understanding its properties and applications is key to leveraging its potential.
Chemically, D-Leucine presents as a white crystalline powder, typically exhibiting a high melting point and good solubility in water and polar organic solvents. Its molecular formula, C6H13NO2, and molar mass of approximately 131.17 g/mol are standard identifiers. The significance of D-Leucine lies in its 'D' configuration, contrasting with the 'L' form found ubiquitously in natural proteins. This difference in stereochemistry allows chemists to design peptides and small molecules with altered enzymatic stability and receptor binding profiles, often leading to improved therapeutic efficacy or reduced side effects.
The applications of D-Leucine are diverse. In peptide synthesis, it serves as a chiral building block for creating peptidomimetics and unnatural peptides. These modified peptides can exhibit enhanced resistance to proteases, prolonging their action in vivo. Furthermore, D-Leucine acts as a crucial pharmaceutical intermediate in the synthesis of various drug candidates. Its role extends to research chemicals, where it is used in studies investigating protein folding, enzyme mechanisms, and metabolic pathways.
For organizations looking to purchase D-Leucine, securing a dependable source is crucial. Partnering with a chemical manufacturer specializing in amino acid derivatives ensures access to consistent quality and reliable supply. When you seek to buy D-Leucine, consider manufacturers that offer comprehensive product specifications and flexible order quantities, from laboratory-scale to bulk industrial requirements. NINGBO INNO PHARMCHEM CO.,LTD. is a prominent supplier dedicated to providing high-purity D-Leucine and related chemical intermediates. We invite you to request a quote and explore how our products can support your next groundbreaking project.
Perspectives & Insights
Molecule Vision 7
“The significance of D-Leucine lies in its 'D' configuration, contrasting with the 'L' form found ubiquitously in natural proteins.”
Alpha Origin 24
“This difference in stereochemistry allows chemists to design peptides and small molecules with altered enzymatic stability and receptor binding profiles, often leading to improved therapeutic efficacy or reduced side effects.”
Future Analyst X
“In peptide synthesis, it serves as a chiral building block for creating peptidomimetics and unnatural peptides.”