For researchers engaged in peptide synthesis, the choice of amino acid derivatives and dipeptides is critical for building complex and functional peptide chains. D-Leucylglycine (CAS 997-05-7) has emerged as a valuable component in this field, offering unique properties that facilitate the creation of novel peptide structures. Its significance stems from its nature as a dipeptide, combining the amino acid D-leucine with glycine.

Peptide synthesis relies on the precise coupling of amino acids, one by one, to form a specific sequence. D-Leucylglycine can be used as a pre-formed dipeptide unit, simplifying certain synthetic routes and potentially improving yields. This approach is particularly useful when constructing peptides that incorporate non-natural amino acids or modified structures. The high purity (≥98%) of D-Leucylglycine provided by reputable manufacturers ensures that unwanted side reactions are minimized, a crucial factor in complex synthesis projects.

The 'D' designation in D-Leucylglycine indicates that the leucine component has a D-configuration, unlike the naturally occurring L-amino acids. Incorporating D-amino acids into peptides can confer several advantageous properties, such as increased resistance to enzymatic degradation in vivo. This makes peptides containing D-Leucylglycine potentially more stable and longer-lasting, a sought-after characteristic for therapeutic peptides.

Researchers often need to buy D-Leucylglycine for various experimental purposes, including the synthesis of enzyme substrates, receptor ligands, and novel biomaterials. The availability of this compound from chemical suppliers as a white powder solid, with clear specifications regarding its molecular formula (C8H16N2O3) and molecular weight (188.22400), aids in experimental design and stoichiometric calculations. When sourcing, looking for suppliers who clearly list synonyms like H-D-LEU-GLY-OH can help ensure you are obtaining the correct isomer.

The price and accessibility of D-Leucylglycine are also considerations for research budgets. While specialized intermediates can be costly, manufacturers in China often provide competitive pricing, making this valuable building block more accessible for academic and industrial research laboratories. It's always beneficial to request a quote and compare options before making a purchase.

In summary, D-Leucylglycine offers peptide chemists a versatile tool for constructing peptides with enhanced stability and unique functionalities. Its role as a dipeptide intermediate, combined with the benefits of D-amino acid incorporation, makes it an indispensable compound for advanced peptide research. For scientists looking to purchase this material, focusing on quality, supplier reliability, and cost-effectiveness will ensure successful synthesis outcomes.